Antibody data
- Antibody Data
- Antigen structure
- References [10]
- Comments [0]
- Validations
- Western blot [3]
- ELISA [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- AF2948 - Provider product page
- Provider
- Novus Biologicals
- Product name
- Goat Polyclonal Serum Amyloid A1/A2 Antibody
- Antibody type
- Polyclonal
- Description
- Antigen Affinity-purified. Detects mouse Serum Amyloid A1/SAA1 and mouse Serum Amyloid A2/SAA2 in direct ELISAs and Western blots. In direct ELISAs, less than 3% cross-reactivity with recombinant human (rh) SAA1, rhSAA2, recombinant mouse (rm) SAA3, and rmSAA4 is observed.
- Reactivity
- Mouse
- Host
- Goat
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 ug
- Concentration
- LYOPH
- Storage
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 degreesC as supplied. 1 month, 2 to 8 degreesC under sterile conditions after reconstitution. 6 months, -20 to -70 degreesC under sterile conditions after reconstitution.
Submitted references Serum amyloid A exhibits pH dependent antibacterial action and contributes to host defense against Staphylococcus aureus cutaneous infection.
Serum Amyloid A Protein as a Potential Biomarker for Severity and Acute Outcome in Traumatic Brain Injury.
Increased hypothalamic microglial activation after viral-induced pneumococcal lung infection is associated with excess serum amyloid A production.
Amyloid deposition in a mouse model humanized at the transthyretin and retinol-binding protein 4 loci.
Serum Amyloid A1 Is an Epithelial Prorestitutive Factor.
Scavenger Receptor A1 Prevents Metastasis of Non-Small Cell Lung Cancer via Suppression of Macrophage Serum Amyloid A1.
Zymosan-mediated inflammation impairs in vivo reverse cholesterol transport.
Transmission of circulating cell-free AA amyloid oligomers in exosomes vectors via a prion-like mechanism.
Role of APAF-1, E-cadherin and peritumoral lymphocytic infiltration in tumour budding in colorectal cancer.
Fish oil increases cholesterol storage in white adipose tissue with concomitant decreases in inflammation, hepatic steatosis, and atherosclerosis in mice.
Zheng H, Li H, Zhang J, Fan H, Jia L, Ma W, Ma S, Wang S, You H, Yin Z, Li X
The Journal of biological chemistry 2020 Feb 28;295(9):2570-2581
The Journal of biological chemistry 2020 Feb 28;295(9):2570-2581
Serum Amyloid A Protein as a Potential Biomarker for Severity and Acute Outcome in Traumatic Brain Injury.
Wicker E, Benton L, George K, Furlow W, Villapol S
BioMed research international 2019;2019:5967816
BioMed research international 2019;2019:5967816
Increased hypothalamic microglial activation after viral-induced pneumococcal lung infection is associated with excess serum amyloid A production.
Wang H, Blackall M, Sominsky L, Spencer SJ, Vlahos R, Churchill M, Bozinovski S
Journal of neuroinflammation 2018 Jul 6;15(1):200
Journal of neuroinflammation 2018 Jul 6;15(1):200
Amyloid deposition in a mouse model humanized at the transthyretin and retinol-binding protein 4 loci.
Li X, Lyu Y, Shen J, Mu Y, Qiang L, Liu L, Araki K, Imbimbo BP, Yamamura KI, Jin S, Li Z
Laboratory investigation; a journal of technical methods and pathology 2018 Apr;98(4):512-524
Laboratory investigation; a journal of technical methods and pathology 2018 Apr;98(4):512-524
Serum Amyloid A1 Is an Epithelial Prorestitutive Factor.
Hinrichs BH, Matthews JD, Siuda D, O'Leary MN, Wolfarth AA, Saeedi BJ, Nusrat A, Neish AS
The American journal of pathology 2018 Apr;188(4):937-949
The American journal of pathology 2018 Apr;188(4):937-949
Scavenger Receptor A1 Prevents Metastasis of Non-Small Cell Lung Cancer via Suppression of Macrophage Serum Amyloid A1.
Zhang Y, Wei Y, Jiang B, Chen L, Bai H, Zhu X, Li X, Zhang H, Yang Q, Ma J, Xu Y, Ben J, Christiani DC, Chen Q
Cancer research 2017 Apr 1;77(7):1586-1598
Cancer research 2017 Apr 1;77(7):1586-1598
Zymosan-mediated inflammation impairs in vivo reverse cholesterol transport.
Malik P, Berisha SZ, Santore J, Agatisa-Boyle C, Brubaker G, Smith JD
Journal of lipid research 2011 May;52(5):951-7
Journal of lipid research 2011 May;52(5):951-7
Transmission of circulating cell-free AA amyloid oligomers in exosomes vectors via a prion-like mechanism.
Tasaki M, Ueda M, Ochiai S, Tanabe Y, Murata S, Misumi Y, Su Y, Sun X, Shinriki S, Jono H, Shono M, Obayashi K, Ando Y
Biochemical and biophysical research communications 2010 Oct 1;400(4):559-62
Biochemical and biophysical research communications 2010 Oct 1;400(4):559-62
Role of APAF-1, E-cadherin and peritumoral lymphocytic infiltration in tumour budding in colorectal cancer.
Zlobec I, Lugli A, Baker K, Roth S, Minoo P, Hayashi S, Terracciano L, Jass JR
The Journal of pathology 2007 Jul;212(3):260-8
The Journal of pathology 2007 Jul;212(3):260-8
Fish oil increases cholesterol storage in white adipose tissue with concomitant decreases in inflammation, hepatic steatosis, and atherosclerosis in mice.
Saraswathi V, Gao L, Morrow JD, Chait A, Niswender KD, Hasty AH
The Journal of nutrition 2007 Jul;137(7):1776-82
The Journal of nutrition 2007 Jul;137(7):1776-82
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Detection of Mouse Serum Amyloid A1/A2 by Western Blot. Detection of Mouse Serum Amyloid A1/A2 by Western Blot.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Detection of Mouse Serum Amyloid A1/A2 by Western Blot. Detection of Mouse Serum Amyloid A1/A2 by Western Blot.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Detection of Mouse Serum Amyloid A1/A2 by Simple WesternTM. Detection of Mouse Serum Amyloid A1/A2 by Simple WesternTM.
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Mouse Serum Amyloid A1/A2 ELISA Standard Curve. Mouse Serum Amyloid A1/A2 ELISA Standard Curve.
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Serum Amyloid A1/A2 in Mouse Liver. Serum Amyloid A1/A2 in Mouse Liver.