Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations
- Western blot [1]
Submit
Validation data
Reference
Comment
Report error
- Product number
- 11-12020-25 - Provider product page
- Provider
- ABEOMICS Inc.
- Product name
- Anti-HOXA9 Antibody
- Antibody type
- Polyclonal
- Description
- HOXA9 is a well-studied member of the HOXA cluster, and it plays a significant role in both normal hematopoiesis and leukemogenesis. HOXA9 is expressed in EC (Endothelial Cells) and its expression is rapidly downregulated during EC activation by inflammatory signals like TNF-alpha (Tumor Necrosis Factor-Alpha) and LPS (lipopolysaccharide) . In humans,HOXA9 was found to be highly expressed and required in some subtypes of leukemia, particularly mixed lineage leukemia (MLL)-rearranged leukemia. The aberrant overexpression of HOXA9 is thought to be associated with poor survival of acute myeloid leukemia (AML) patients.
- Reactivity
- Human
- Host
- Rabbit
- Antigen sequence
A partial length recombinant HOXA9
protein (amino acids 63-272) was us
ed as the immunogen for this antibo
dy.- Vial size
- 25 µg
- Concentration
- 0.5 mg/ml
- Storage
- Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeat freezing and thawing
No comments: Submit comment
Supportive validation
- Submitted by
- ABEOMICS Inc. (provider)
- Main image
- Experimental details
- Expression analysis of HOXA9. Anti-HOXA9 antibody (11-12020) was used at 1 µg/ml on h Liver lysate.