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Learn19929-1-AP
antibody from Proteintech Group
Targeting: HEY1
bHLHb31, CHF-2, CHF2, HERP2, HESR-1, HESR1, HRT-1
Western blot
ELISAAntibody data
- Antibody Data
- Antigen structure
- References [24]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [2]
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- Product number
- 19929-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#19929-1-AP, RRID:AB_10646438
- Product name
- HEY1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated HEY1 antibody (Cat. #19929-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IP, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Generation and characterization of cardiac valve endothelial-like cells from human pluripotent stem cells.
Obesity Impairs Embryonic Myogenesis by Enhancing BMP Signaling within the Dermomyotome.
hPER3 promotes adipogenesis via hHSP90AA1-mediated inhibition of Notch1 pathway.
Reciprocal activation of HEY1 and NOTCH4 under SOX2 control promotes EMT in head and neck squamous cell carcinoma.
Reduced expression of ppGalNAc-T4 promotes proliferation of human breast cancer cells.
ST3Gal IV Mediates the Growth and Proliferation of Cervical Cancer Cells In Vitro and In Vivo Via the Notch/p21/CDKs Pathway.
Notch1 signaling mediated dysfunction of bone marrow mesenchymal stem cells derived from cyanotic congenital heart disease.
A Noncoding Regulatory RNAs Network Driven by Circ-CDYL Acts Specifically in the Early Stages Hepatocellular Carcinoma.
miR-214-5p suppresses the proliferation, migration and invasion of trophoblast cells in pre-eclampsia by targeting jagged 1 to inhibit notch signaling pathway.
JAG2/Notch2 inhibits intervertebral disc degeneration by modulating cell proliferation, apoptosis, and extracellular matrix.
Salidroside suppresses the metastasis of hepatocellular carcinoma cells by inhibiting the activation of the Notch1 signaling pathway.
Undifferentiated spermatogonia regulate Cyp26b1 expression through NOTCH signaling and drive germ cell differentiation.
MicroRNA-34a attenuates VEGF-mediated retinal angiogenesis via targeting Notch1.
Modification of α2,6-sialylation mediates the invasiveness and tumorigenicity of non-small cell lung cancer cells in vitro and in vivo via Notch1/Hes1/MMPs pathway.
MDM2 Contributes to High Glucose-Induced Glomerular Mesangial Cell Proliferation and Extracellular Matrix Accumulation via Notch1.
miR-150 enhances apoptotic and anti-tumor effects of paclitaxel in paclitaxel-resistant ovarian cancer cells by targeting Notch3.
Luteolin suppresses gastric cancer progression by reversing epithelial-mesenchymal transition via suppression of the Notch signaling pathway.
MicroRNA-136 inhibits cancer stem cell activity and enhances the anti-tumor effect of paclitaxel against chemoresistant ovarian cancer cells by targeting Notch3.
Mammalian Numb protein antagonizes Notch by controlling postendocytic trafficking of the Notch ligand Delta-like 4.
The NOTCH Ligand JAG1 Regulates GDNF Expression in Sertoli Cells.
microRNA-23a, -27a and -24 synergistically regulate JAK1/Stat3 cascade and serve as novel therapeutic targets in human acute erythroid leukemia.
Notch3-specific inhibition using siRNA knockdown or GSI sensitizes paclitaxel-resistant ovarian cancer cells.
EGCG Attenuates Uric Acid-Induced Inflammatory and Oxidative Stress Responses by Medicating the NOTCH Pathway.
Cathepsin K-mediated Notch1 activation contributes to neovascularization in response to hypoxia.
Cheng L, Xie M, Qiao W, Song Y, Zhang Y, Geng Y, Xu W, Wang L, Wang Z, Huang K, Dong N, Sun Y
Communications biology 2021 Sep 6;4(1):1039
Communications biology 2021 Sep 6;4(1):1039
Obesity Impairs Embryonic Myogenesis by Enhancing BMP Signaling within the Dermomyotome.
Zhao L, Law NC, Gomez NA, Son J, Gao Y, Liu X, de Avila JM, Zhu MJ, Du M
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2021 Nov;8(22):e2102157
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2021 Nov;8(22):e2102157
hPER3 promotes adipogenesis via hHSP90AA1-mediated inhibition of Notch1 pathway.
Wan X, Zhu L, Zhao L, Peng L, Xiong J, Yang W, Yuan J, Liang F, Zhang K, Chen K
Cell death & disease 2021 Mar 19;12(4):301
Cell death & disease 2021 Mar 19;12(4):301
Reciprocal activation of HEY1 and NOTCH4 under SOX2 control promotes EMT in head and neck squamous cell carcinoma.
Fukusumi T, Guo TW, Ren S, Haft S, Liu C, Sakai A, Ando M, Saito Y, Sadat S, Califano JA
International journal of oncology 2021 Feb;58(2):226-237
International journal of oncology 2021 Feb;58(2):226-237
Reduced expression of ppGalNAc-T4 promotes proliferation of human breast cancer cells.
Wu Q, Xie X, Zhang K, Niang B, Liu Y, Zhang C, Huang T, Huang H, Li W, Zhang J, Liu Y
Cell biology international 2021 Feb;45(2):320-333
Cell biology international 2021 Feb;45(2):320-333
ST3Gal IV Mediates the Growth and Proliferation of Cervical Cancer Cells In Vitro and In Vivo Via the Notch/p21/CDKs Pathway.
Wu Y, Chen X, Dong W, Xu Z, Jian Y, Xu C, Zhang L, Wei A, Yu X, Wang S, Wang Y, Liu G, Sun X, Wang S
Frontiers in oncology 2020;10:540332
Frontiers in oncology 2020;10:540332
Notch1 signaling mediated dysfunction of bone marrow mesenchymal stem cells derived from cyanotic congenital heart disease.
Wang T, Xing J, Ying Y, Tang H, Li J, Wei Y, Zhang H
Biochemical and biophysical research communications 2020 Jul 5;527(4):847-853
Biochemical and biophysical research communications 2020 Jul 5;527(4):847-853
A Noncoding Regulatory RNAs Network Driven by Circ-CDYL Acts Specifically in the Early Stages Hepatocellular Carcinoma.
Wei Y, Chen X, Liang C, Ling Y, Yang X, Ye X, Zhang H, Yang P, Cui X, Ren Y, Xin X, Li H, Wang R, Wang W, Jiang F, Liu S, Ding J, Zhang B, Li L, Wang H
Hepatology (Baltimore, Md.) 2020 Jan;71(1):130-147
Hepatology (Baltimore, Md.) 2020 Jan;71(1):130-147
miR-214-5p suppresses the proliferation, migration and invasion of trophoblast cells in pre-eclampsia by targeting jagged 1 to inhibit notch signaling pathway.
Gong F, Chai W, Wang J, Cheng H, Shi Y, Cui L, Jia G
Acta histochemica 2020 Apr;122(3):151527
Acta histochemica 2020 Apr;122(3):151527
JAG2/Notch2 inhibits intervertebral disc degeneration by modulating cell proliferation, apoptosis, and extracellular matrix.
Long J, Wang X, Du X, Pan H, Wang J, Li Z, Liu H, Li X, Zheng Z
Arthritis research & therapy 2019 Oct 16;21(1):213
Arthritis research & therapy 2019 Oct 16;21(1):213
Salidroside suppresses the metastasis of hepatocellular carcinoma cells by inhibiting the activation of the Notch1 signaling pathway.
Lu L, Liu S, Dong Q, Xin Y
Molecular medicine reports 2019 Jun;19(6):4964-4972
Molecular medicine reports 2019 Jun;19(6):4964-4972
Undifferentiated spermatogonia regulate Cyp26b1 expression through NOTCH signaling and drive germ cell differentiation.
Parekh PA, Garcia TX, Waheeb R, Jain V, Gandhi P, Meistrich ML, Shetty G, Hofmann MC
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Jul;33(7):8423-8435
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Jul;33(7):8423-8435
MicroRNA-34a attenuates VEGF-mediated retinal angiogenesis via targeting Notch1.
Shi S, Jin Y, Song H, Chen X
Biochemistry and cell biology = Biochimie et biologie cellulaire 2019 Aug;97(4):423-430
Biochemistry and cell biology = Biochimie et biologie cellulaire 2019 Aug;97(4):423-430
Modification of α2,6-sialylation mediates the invasiveness and tumorigenicity of non-small cell lung cancer cells in vitro and in vivo via Notch1/Hes1/MMPs pathway.
Yuan Q, Chen X, Han Y, Lei T, Wu Q, Yu X, Wang L, Fan Z, Wang S
International journal of cancer 2018 Nov 1;143(9):2319-2330
International journal of cancer 2018 Nov 1;143(9):2319-2330
MDM2 Contributes to High Glucose-Induced Glomerular Mesangial Cell Proliferation and Extracellular Matrix Accumulation via Notch1.
Lei CT, Tang H, Ye C, You CQ, Zhang J, Zhang CY, Xiong W, Su H, Zhang C
Scientific reports 2017 Sep 4;7(1):10393
Scientific reports 2017 Sep 4;7(1):10393
miR-150 enhances apoptotic and anti-tumor effects of paclitaxel in paclitaxel-resistant ovarian cancer cells by targeting Notch3.
Kim TH, Jeong JY, Park JY, Kim SW, Heo JH, Kang H, Kim G, An HJ
Oncotarget 2017 Sep 22;8(42):72788-72800
Oncotarget 2017 Sep 22;8(42):72788-72800
Luteolin suppresses gastric cancer progression by reversing epithelial-mesenchymal transition via suppression of the Notch signaling pathway.
Zang MD, Hu L, Fan ZY, Wang HX, Zhu ZL, Cao S, Wu XY, Li JF, Su LP, Li C, Zhu ZG, Yan M, Liu BY
Journal of translational medicine 2017 Feb 27;15(1):52
Journal of translational medicine 2017 Feb 27;15(1):52
MicroRNA-136 inhibits cancer stem cell activity and enhances the anti-tumor effect of paclitaxel against chemoresistant ovarian cancer cells by targeting Notch3.
Jeong JY, Kang H, Kim TH, Kim G, Heo JH, Kwon AY, Kim S, Jung SG, An HJ
Cancer letters 2017 Feb 1;386:168-178
Cancer letters 2017 Feb 1;386:168-178
Mammalian Numb protein antagonizes Notch by controlling postendocytic trafficking of the Notch ligand Delta-like 4.
Shao X, Ding Z, Zhao M, Liu K, Sun H, Chen J, Liu X, Zhang Y, Hong Y, Li H, Li H
The Journal of biological chemistry 2017 Dec 15;292(50):20628-20643
The Journal of biological chemistry 2017 Dec 15;292(50):20628-20643
The NOTCH Ligand JAG1 Regulates GDNF Expression in Sertoli Cells.
Garcia TX, Parekh P, Gandhi P, Sinha K, Hofmann MC
Stem cells and development 2017 Apr 15;26(8):585-598
Stem cells and development 2017 Apr 15;26(8):585-598
microRNA-23a, -27a and -24 synergistically regulate JAK1/Stat3 cascade and serve as novel therapeutic targets in human acute erythroid leukemia.
Su R, Dong L, Zou D, Zhao H, Ren Y, Li F, Yi P, Li L, Zhu Y, Ma Y, Wang J, Wang F, Yu J
Oncogene 2016 Nov 17;35(46):6001-6014
Oncogene 2016 Nov 17;35(46):6001-6014
Notch3-specific inhibition using siRNA knockdown or GSI sensitizes paclitaxel-resistant ovarian cancer cells.
Kang H, Jeong JY, Song JY, Kim TH, Kim G, Huh JH, Kwon AY, Jung SG, An HJ
Molecular carcinogenesis 2016 Jul;55(7):1196-209
Molecular carcinogenesis 2016 Jul;55(7):1196-209
EGCG Attenuates Uric Acid-Induced Inflammatory and Oxidative Stress Responses by Medicating the NOTCH Pathway.
Xie H, Sun J, Chen Y, Zong M, Li S, Wang Y
Oxidative medicine and cellular longevity 2015;2015:214836
Oxidative medicine and cellular longevity 2015;2015:214836
Cathepsin K-mediated Notch1 activation contributes to neovascularization in response to hypoxia.
Jiang H, Cheng XW, Shi GP, Hu L, Inoue A, Yamamura Y, Wu H, Takeshita K, Li X, Huang Z, Song H, Asai M, Hao CN, Unno K, Koike T, Oshida Y, Okumura K, Murohara T, Kuzuya M
Nature communications 2014 Jun 4;5:3838
Nature communications 2014 Jun 4;5:3838
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- DU 145 cells were subjected to SDS PAGE followed by western blot with 19929-1-AP(HEY1 antibody) at dilution of 1:3000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human brain using 19929-1-AP(HEY1 antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The HEY1 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human HEY1. This antibody recognizes human,mouse,rat antigen. The HEY1 antibody has been validated for the following applications: ELISA, WB, IHC analysis.
