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Protein structure
MYCN
MYCN proto-oncogene, bHLH transcription factorbHLHe37, MYCNOT, N-myc, NMYC
This gene is a member of the MYC family and encodes a protein with a basic helix-loop-helix (bHLH) domain. This protein is located in the nucleus and must dimerize with another bHLH protein in order to bind DNA. Amplification of this gene is associated with a variety of tumors, most notably neuroblastomas. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2014]
Top validated antibodies |
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| Novus Biologicals |  NB200-109 |
5 references | Monoclonal |
WB
ICC
IP
FC
GS
ChIP
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| GeneTex | GTX20057 |
Monoclonal |
WB
ICC
IP
FC
GS
ChIP
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| Proteintech Group | 10159-2-AP |
12 references | Polyclonal |
WB
EL
IHC
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| antibodies-online | ABIN152254 |
3 references | Monoclonal |
WB
ICC
IP
FC
GS
ChIP
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| Cell Signaling Technology, Inc | 84406 |
Monoclonal |
WB
ICC
IP
FC
ChIP
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