Antibody data
- Antibody Data
- Antigen structure
- References [4]
- Comments [0]
- Validations
- ELISA [1]
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Validation data
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- Product number
- H00130497-M10 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#H00130497-M10, RRID:AB_546677
- Product name
- Mouse Monoclonal OSR1 Antibody
- Antibody type
- Monoclonal
- Description
- IgG purified. OSR1 - odd-skipped related 1 (Drosophila)
- Reactivity
- Human, Mouse
- Host
- Mouse
- Isotype
- IgG
- Vial size
- 0.1 mg
- Storage
- Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Submitted references Decreased KLHL3 expression is involved in the pathogenesis of pseudohypoaldosteronism type II caused by cullin 3 mutation in vivo.
Metformin increases urinary sodium excretion by reducing phosphorylation of the sodium-chloride cotransporter.
Impaired degradation of medullary WNK4 in the kidneys of KLHL2 knockout mice.
WNK4 is the major WNK positively regulating NCC in the mouse kidney.
Yoshida S, Araki Y, Mori T, Sasaki E, Kasagi Y, Isobe K, Susa K, Inoue Y, Bomont P, Okado T, Rai T, Uchida S, Sohara E
Clinical and experimental nephrology 2018 Dec;22(6):1251-1257
Clinical and experimental nephrology 2018 Dec;22(6):1251-1257
Metformin increases urinary sodium excretion by reducing phosphorylation of the sodium-chloride cotransporter.
Hashimoto H, Nomura N, Shoda W, Isobe K, Kikuchi H, Yamamoto K, Fujimaru T, Ando F, Mori T, Okado T, Rai T, Uchida S, Sohara E
Metabolism: clinical and experimental 2018 Aug;85:23-31
Metabolism: clinical and experimental 2018 Aug;85:23-31
Impaired degradation of medullary WNK4 in the kidneys of KLHL2 knockout mice.
Kasagi Y, Takahashi D, Aida T, Nishida H, Nomura N, Zeniya M, Mori T, Sasaki E, Ando F, Rai T, Uchida S, Sohara E
Biochemical and biophysical research communications 2017 May 27;487(2):368-374
Biochemical and biophysical research communications 2017 May 27;487(2):368-374
WNK4 is the major WNK positively regulating NCC in the mouse kidney.
Takahashi D, Mori T, Nomura N, Khan MZ, Araki Y, Zeniya M, Sohara E, Rai T, Sasaki S, Uchida S
Bioscience reports 2014 May 9;34(3)
Bioscience reports 2014 May 9;34(3)
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Supportive validation
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- Novus Biologicals (provider)
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- Experimental details
- Sandwich ELISA: OSR1 Antibody (1G9) [H00130497-M10] - Detection limit for recombinant GST tagged OSR1 is approximately 1ng/ml as a capture antibody.