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Protein structure
IL27
Interleukin 27IL-27, IL-27A, IL27A, IL27p28, IL30, MGC71873, p28
The protein encoded by this gene is one of the subunits of a heterodimeric cytokine complex. This protein is related to interleukin 12A (IL12A). It interacts with Epstein-Barr virus induced gene 3 (EBI3), a protein similar to interleukin 12B (IL12B), and forms a complex that has been shown to drive rapid expansion of naive but not memory CD4(+) T cells. The complex is also found to synergize strongly with interleukin 12 to trigger interferon gamma (IFNG) production of naive CD4(+) T cells. The biological effects of this cytokine are mediated by the class I cytokine receptor (WSX1/TCRR). [provided by RefSeq, Jul 2008]
Top validated antibodies |
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| R&D Systems |  AF2526 |
10 references | Polyclonal |
WB
EL
BN
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| Proteintech Group | 66164-1-Ig |
1 references | Monoclonal |
WB
EL
IHC
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| Novus Biologicals | AF2526 |
10 references | Polyclonal |
WB
BN
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| antibodies-online | ABIN500000 |
1 references | Polyclonal |
WB
EL
ICC
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| Abnova Corporation | PAB13199 |
3 references | Polyclonal |
WB
ICC
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