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PER3
Period circadian regulator 3This gene is a member of the Period family of genes and is expressed in a circadian pattern in the suprachiasmatic nucleus, the primary circadian pacemaker in the mammalian brain. Genes in this family encode components of the circadian rhythms of locomotor activity, metabolism, and behavior. This gene is upregulated by CLOCK/ARNTL heterodimers but then represses this upregulation in a feedback loop using PER/CRY heterodimers to interact with CLOCK/ARNTL. Polymorphisms in this gene have been linked to sleep disorders. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2014]
Top validated antibodies |
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| Invitrogen Antibodies |  MA5-31839 |
Monoclonal |
WB
EL
ICC
IHC
FC
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| Biorbyt | orb229810 |
Monoclonal |
WB
EL
ICC
IHC
FC
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| Proteintech Group | 12550-1-AP |
2 references | Polyclonal |
WB
EL
ICC
IHC
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| antibodies-online | ABIN4881222 |
Monoclonal |
WB
EL
ICC
IHC
FC
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| NovoPro Bioscience Inc. | 113713 |
Polyclonal |
WB
EL
ICC
IHC
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