KCNK13

Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a potassium channel containing two pore-forming domains. This protein is an open channel that can be stimulated by arachidonic acid and inhibited by the anesthetic halothane. [provided by RefSeq, Jul 2013]

Description

Potassium two pore domain channel subfamily K member 13

Tissue specificity

Tissue enhanced (choroid plexus, parathyroid gland, testis)

Subcell location

Nuclear speckles, Cell Junctions

Predicted location

Membrane

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted membrane proteins
Voltage-gated ion channels

Chromosome

14 (90061994 - 90185853)

Ensembl ID

ENSG00000152315  (ver. 103.38)

Orthologs

Mouse Kcnk13: ENSMUSG00000045404

UniProt

Q9HB14

neXtProt

NX_Q9HB14

Human splice variants
Mouse splice variants

Protein structure