Antibody data
- Antibody Data
- Antigen structure
- References [20]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Immunohistochemistry [1]
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- Product number
- 11058-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#11058-1-AP, RRID:AB_2152167
- Product name
- NONO antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated NONO antibody (Cat. #11058-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: FC, IF, IHC, IP, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references AC016745.3 Regulates the Transcription of AR Target Genes by Antagonizing NONO.
Expression of Long Non-coding RNA RGD1566344 in the Brain Cortex of Male Mice After Focal Cerebral Ischemia-Reperfusion and the Neuroprotective Effect of a Non-coding RNA RGD1566344 Inhibitor.
Targeting the p300/NONO axis sensitizes melanoma cells to BRAF inhibitors.
OGA is associated with deglycosylation of NONO and the KU complex during DNA damage repair.
The regulation of NONO by USP11 via deubiquitination is linked to the proliferation of melanoma cells.
The transcribed ultraconserved element uc.51 promotes the proliferation and metastasis of breast cancer by stabilizing NONO.
Interfering MSN-NONO complex-activated CREB signaling serves as a therapeutic strategy for triple-negative breast cancer.
Long non-coding RNA SSTR5-AS1 facilitates gemcitabine resistance via stabilizing NONO in gallbladder carcinoma.
Splicing Regulator p54nrb /Non-POU Domain-Containing Octamer-Binding Protein Enhances Carcinogenesis Through Oncogenic Isoform Switch of MYC Box-Dependent Interacting Protein 1 in Hepatocellular Carcinoma.
Long non-coding RNA LINC-PINT attenuates paclitaxel resistance in triple-negative breast cancer cells via targeting the RNA-binding protein NONO.
Silver Nanoparticles Compromise Female Embryonic Stem Cell Differentiation through Disturbing X Chromosome Inactivation.
Characterization of telomeric repeat-containing RNA (TERRA) localization and protein interactions in primordial germ cells of the mouse†.
A variant of death-receptor 3 associated with rheumatoid arthritis interferes with apoptosis-induction of T cell.
The Long Noncoding RNA NEAT1 Exerts Antihantaviral Effects by Acting as Positive Feedback for RIG-I Signaling.
Synergistic upregulation of NONO and PSPC1 regulates Sertoli cell response to MEHP via modulation of ALDH1A1 signaling.
Distinct Protein Expression Profiles of Solid-Pseudopapillary Neoplasms of the Pancreas.
The transcription-splicing protein NonO/p54nrb and three NonO-interacting proteins bind to distal enhancer region and augment rhodopsin expression.
14-3-3ε mediates the cell fate decision-making pathways in response of hepatocellular carcinoma to Bleomycin-induced DNA damage.
Proteomic dissection of cell type-specific H2AX-interacting protein complex associated with hepatocellular carcinoma.
Biotin tagging coupled with amino acid-coded mass tagging for efficient and precise screening of interaction proteome in mammalian cells.
Lu Y, Wan X, Huang W, Zhang L, Luo J, Li D, Huang Y, Li Y, Xu Y
Life (Basel, Switzerland) 2021 Nov 9;11(11)
Life (Basel, Switzerland) 2021 Nov 9;11(11)
Expression of Long Non-coding RNA RGD1566344 in the Brain Cortex of Male Mice After Focal Cerebral Ischemia-Reperfusion and the Neuroprotective Effect of a Non-coding RNA RGD1566344 Inhibitor.
Zhang J, Rui Y, Gao M, Wang L, Yan BC
Cellular and molecular neurobiology 2021 May;41(4):705-716
Cellular and molecular neurobiology 2021 May;41(4):705-716
Targeting the p300/NONO axis sensitizes melanoma cells to BRAF inhibitors.
Zhang F, Tang X, Fan S, Liu X, Sun J, Ju C, Liang Y, Liu R, Zhou R, Yu B, Zhang C, Zhang Z, Kang T, Huang G, Lv XB
Oncogene 2021 Jun;40(24):4137-4150
Oncogene 2021 Jun;40(24):4137-4150
OGA is associated with deglycosylation of NONO and the KU complex during DNA damage repair.
Cui Y, Xie R, Zhang X, Liu Y, Hu Y, Li Y, Liu X, Yu X, Wu C
Cell death & disease 2021 Jun 16;12(7):622
Cell death & disease 2021 Jun 16;12(7):622
The regulation of NONO by USP11 via deubiquitination is linked to the proliferation of melanoma cells.
Feng P, Li L, Dai J, Zhou L, Liu J, Zhao J, Li X, Ling N, Qiu S, Zhang L, Xie T, Chen Y, Donovan MJ, Peng T, Song J, Ye M
Journal of cellular and molecular medicine 2021 Feb;25(3):1507-1517
Journal of cellular and molecular medicine 2021 Feb;25(3):1507-1517
The transcribed ultraconserved element uc.51 promotes the proliferation and metastasis of breast cancer by stabilizing NONO.
Shi X, Huang X, Chen R, Li Y, Xu Y, Zhang W, Zhu Q, Zha X, Wang J
Clinical & experimental metastasis 2021 Dec;38(6):551-571
Clinical & experimental metastasis 2021 Dec;38(6):551-571
Interfering MSN-NONO complex-activated CREB signaling serves as a therapeutic strategy for triple-negative breast cancer.
Qin Y, Chen W, Jiang G, Zhou L, Yang X, Li H, He X, Wang HL, Zhou YB, Huang S, Liu S
Science advances 2020 Feb;6(8):eaaw9960
Science advances 2020 Feb;6(8):eaaw9960
Long non-coding RNA SSTR5-AS1 facilitates gemcitabine resistance via stabilizing NONO in gallbladder carcinoma.
Xue Z, Yang B, Xu Q, Zhu X, Qin G
Biochemical and biophysical research communications 2020 Feb 19;522(4):952-959
Biochemical and biophysical research communications 2020 Feb 19;522(4):952-959
Splicing Regulator p54nrb /Non-POU Domain-Containing Octamer-Binding Protein Enhances Carcinogenesis Through Oncogenic Isoform Switch of MYC Box-Dependent Interacting Protein 1 in Hepatocellular Carcinoma.
Hu Z, Dong L, Li S, Li Z, Qiao Y, Li Y, Ding J, Chen Z, Wu Y, Wang Z, Huang S, Gao Q, Zhao Y, He X
Hepatology (Baltimore, Md.) 2020 Aug;72(2):548-568
Hepatology (Baltimore, Md.) 2020 Aug;72(2):548-568
Long non-coding RNA LINC-PINT attenuates paclitaxel resistance in triple-negative breast cancer cells via targeting the RNA-binding protein NONO.
Chen J, Zhu M, Zou L, Xia J, Huang J, Deng Q, Xu R
Acta biochimica et biophysica Sinica 2020 Aug 5;52(8):801-809
Acta biochimica et biophysica Sinica 2020 Aug 5;52(8):801-809
Silver Nanoparticles Compromise Female Embryonic Stem Cell Differentiation through Disturbing X Chromosome Inactivation.
Zhang J, Chen Y, Gao M, Wang Z, Liu R, Xia T, Liu S
ACS nano 2019 Feb 26;13(2):2050-2061
ACS nano 2019 Feb 26;13(2):2050-2061
Characterization of telomeric repeat-containing RNA (TERRA) localization and protein interactions in primordial germ cells of the mouse†.
Brieño-Enríquez MA, Moak SL, Abud-Flores A, Cohen PE
Biology of reproduction 2019 Apr 1;100(4):950-962
Biology of reproduction 2019 Apr 1;100(4):950-962
A variant of death-receptor 3 associated with rheumatoid arthritis interferes with apoptosis-induction of T cell.
Hashiramoto A, Konishi Y, Murayama K, Kawasaki H, Yoshida K, Tsumiyama K, Tanaka K, Mizuhara M, Shiotsuki T, Kitamura H, Komai K, Kimura T, Yagita H, Shiozawa K, Shiozawa S
The Journal of biological chemistry 2018 Feb 9;293(6):1933-1943
The Journal of biological chemistry 2018 Feb 9;293(6):1933-1943
The Long Noncoding RNA NEAT1 Exerts Antihantaviral Effects by Acting as Positive Feedback for RIG-I Signaling.
Ma H, Han P, Ye W, Chen H, Zheng X, Cheng L, Zhang L, Yu L, Wu X, Xu Z, Lei Y, Zhang F
Journal of virology 2017 May 1;91(9)
Journal of virology 2017 May 1;91(9)
Synergistic upregulation of NONO and PSPC1 regulates Sertoli cell response to MEHP via modulation of ALDH1A1 signaling.
Dong BW, Jin XH, Yan CY, Yang T, Cai GQ, Lu J
FEBS letters 2017 Mar;591(6):914-923
FEBS letters 2017 Mar;591(6):914-923
Distinct Protein Expression Profiles of Solid-Pseudopapillary Neoplasms of the Pancreas.
Park M, Lim JS, Lee HJ, Na K, Lee MJ, Kang CM, Paik YK, Kim H
Journal of proteome research 2015 Aug 7;14(8):3007-14
Journal of proteome research 2015 Aug 7;14(8):3007-14
The transcription-splicing protein NonO/p54nrb and three NonO-interacting proteins bind to distal enhancer region and augment rhodopsin expression.
Yadav SP, Hao H, Yang HJ, Kautzmann MA, Brooks M, Nellissery J, Klocke B, Seifert M, Swaroop A
Human molecular genetics 2014 Apr 15;23(8):2132-44
Human molecular genetics 2014 Apr 15;23(8):2132-44
14-3-3ε mediates the cell fate decision-making pathways in response of hepatocellular carcinoma to Bleomycin-induced DNA damage.
Tang S, Bao H, Zhang Y, Yao J, Yang P, Chen X
PloS one 2013;8(3):e55268
PloS one 2013;8(3):e55268
Proteomic dissection of cell type-specific H2AX-interacting protein complex associated with hepatocellular carcinoma.
Yang X, Zou P, Yao J, Yun D, Bao H, Du R, Long J, Chen X
Journal of proteome research 2010 Mar 5;9(3):1402-15
Journal of proteome research 2010 Mar 5;9(3):1402-15
Biotin tagging coupled with amino acid-coded mass tagging for efficient and precise screening of interaction proteome in mammalian cells.
He YF, Bao HM, Xiao XF, Zuo S, Du RY, Tang SW, Yang PY, Chen X
Proteomics 2009 Dec;9(24):5414-24
Proteomics 2009 Dec;9(24):5414-24
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- MCF7 cells were subjected to SDS PAGE followed by western blot with 11058-1-AP(NONO antibody) at dilution of 1:1000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of HepG2 cells, using NONO antibody 11058-1-AP at 1:100 dilution and FITC-labeled donkey anti-rabbit IgG(green). Blue pseudocolor = DAPI (fluorescent DNA dye).
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human colon cancer using 11058-1-AP(NONO antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue