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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- PAB3386 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#PAB3386, RRID:AB_1580237
- Product name
- ROR2 polyclonal antibody
- Antibody type
- Polyclonal
- Antigen
- A synthetic peptide (conjugated with KLH) corresponding to C-terminus of human ROR2.
- Reactivity
- Human
- Host
- Rabbit
- Vial size
- 400 μl
- Storage
- Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Submitted references Wnt5a involved in regulation of the biological behavior of hepatocellular carcinoma.
Loss of Wnt5a and Ror2 protein in hepatocellular carcinoma associated with poor prognosis.
Dominant mutations in ROR2, encoding an orphan receptor tyrosine kinase, cause brachydactyly type B.
Mutation of the gene encoding the ROR2 tyrosine kinase causes autosomal recessive Robinow syndrome.
Recessive Robinow syndrome, allelic to dominant brachydactyly type B, is caused by mutation of ROR2.
Bi L, Liu X, Wang C, Cao Y, Mao R, Li P, Geng M
International journal of clinical and experimental pathology 2014;7(3):987-95
International journal of clinical and experimental pathology 2014;7(3):987-95
Loss of Wnt5a and Ror2 protein in hepatocellular carcinoma associated with poor prognosis.
Geng M, Cao YC, Chen YJ, Jiang H, Bi LQ, Liu XH
World journal of gastroenterology 2012 Mar 28;18(12):1328-38
World journal of gastroenterology 2012 Mar 28;18(12):1328-38
Dominant mutations in ROR2, encoding an orphan receptor tyrosine kinase, cause brachydactyly type B.
Oldridge M, Fortuna AM, Maringa M, Propping P, Mansour S, Pollitt C, DeChiara TM, Kimble RB, Valenzuela DM, Yancopoulos GD, Wilkie AO
Nature genetics 2000 Mar;24(3):275-8
Nature genetics 2000 Mar;24(3):275-8
Mutation of the gene encoding the ROR2 tyrosine kinase causes autosomal recessive Robinow syndrome.
van Bokhoven H, Celli J, Kayserili H, van Beusekom E, Balci S, Brussel W, Skovby F, Kerr B, Percin EF, Akarsu N, Brunner HG
Nature genetics 2000 Aug;25(4):423-6
Nature genetics 2000 Aug;25(4):423-6
Recessive Robinow syndrome, allelic to dominant brachydactyly type B, is caused by mutation of ROR2.
Afzal AR, Rajab A, Fenske CD, Oldridge M, Elanko N, Ternes-Pereira E, Tüysüz B, Murday VA, Patton MA, Wilkie AO, Jeffery S
Nature genetics 2000 Aug;25(4):419-22
Nature genetics 2000 Aug;25(4):419-22
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Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Western blot analysis of ROR2 (arrow) using ROR2 polyclonal antibody (Cat # PAB3386).293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the ROR2 gene (Lane 2).
Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Formalin-fixed and paraffin-embedded human cancer tissue reacted with ROR2 polyclonal antibody (Cat # PAB3386) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry ; clinical relevance has not been evaluated. BC = breast carcinoma.
- Validation comment
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
