Explore
Validate
LearnTissue expression
Cell line expression
Protein structure
AFP
Alpha fetoproteinFETA, HPAFP
This gene encodes alpha-fetoprotein, a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha-fetoprotein expression in adults is often associated with hepatocarcinoma and with teratoma, and has prognostic value for managing advanced gastric cancer. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly. [provided by RefSeq, Oct 2019]
Top validated antibodies |
|||||
| Novus Biologicals |  H00000174-M01 |
4 references | Monoclonal |
WB
EL
ICC
IP
IHC
FA
|
|
| Proteintech Group | 14550-1-AP |
62 references | Polyclonal |
WB
EL
ICC
IP
IHC
|
|
| antibodies-online | ABIN394088 |
5 references | Monoclonal |
WB
EL
ICC
IP
IHC
|
|
| Invitrogen Antibodies | PA5-16658 |
4 references | Polyclonal |
WB
ICC
IHC
FC
|
|
| Abnova Corporation | H00000174-M01 |
2 references | Monoclonal |
WB
EL
ICC
IP
|
|
All Antibodies
Filters
Enhanced validation Supportive data in Antibodypedia Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider