11-1021

antibody from ABEOMICS Inc.
Targeting: DEPTOR DEP.6, DEPDC6, FLJ12428
Provider product page for 11-1021

Antibody data

Product number
11-1021 - Provider product page
Provider
ABEOMICS Inc.
Product name
Anti-DEPTOR/DEPDC6 Antibody
Antibody type
Polyclonal
Description
DEPTOR is an mTOR inhibitor whose expression is negatively regulated by mTOR. DEPTOR expression is required to maintain PI3K and Akt activation and to inhibit apoptosis. DEPTOR is expressed in different microvascular ECs (endothelial cells). It plays a key role in maintaining stem cell pluripotency by limiting mTOR activity in undifferentiated embryonic stem cells (ESCs). It is overexpressed in RPMI-8226 human multiple myeloma cells, and plays an important role in maintaining cell survival.
Reactivity
Human
Host
Rabbit
Antigen sequence
A partial length recombinant DEPTOR
protein (amino acids 111-301) was
used as the immunogen for this anti
body.
Vial size
100 µg
Concentration
0.5 mg/ml
Storage
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeat freezing and thawing
DEPTOR protein structure - 11-1021 shown in red.