Explore
Validate
LearnTissue expression
Cell line expression
Protein structure
FRMPD2
FERM and PDZ domain containing 2MGC35285, PDZD5C, PDZK5C
This gene encodes a peripheral membrane protein and is located in a region of chromosome 10q that contains a segmental duplication. This copy of the gene is full-length and is in the telomeric duplicated region. Two other more centromerically proximal copies of the gene are partial and may represent pseudogenes. This full-length gene appears to function in the establishment and maintenance of cell polarization. The protein is recruited to cell-cell junctions in an E-cadherin-dependent manner, and is selectively localized at the basolateral membrane in polarized epithelial cells. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2009]
Top validated antibodies |
|||||
| OriGene |  TA306863 |
1 references | Polyclonal |
WB
IHC
|
|
| GeneTex | GTX85236 |
Polyclonal |
WB
EL
IHC
|
||
| Novus Biologicals | NBP1-77083 |
Polyclonal |
WB
EL
IHC
|
||
| Boster Biological Technology | A12236 |
Polyclonal |
WB
EL
IHC
|
||
| antibodies-online | ABIN1031387 |
Polyclonal |
WB
EL
IHC
|
||
All Antibodies
Filters
Enhanced validation Supportive data in Antibodypedia Data presented on provider website
Data in Antibodypedia (inconclusive) Recommended by provider