ABIN657143

antibody from antibodies-online

Targeting: AFG3L2 SCA28, SPAX5

Western blot (Data presented on provider website)

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

ABIN657143

Provider

antibodies-online

Product name

anti-AFG3 ATPase Family Gene 3-Like 2 (S. Cerevisiae) (AFG3L2) (N-Term), (AA 52-80) antibody

Antibody type

Polyclonal

Antigen

This AFG3L2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 52-80 AA from the N-terminal region of human AFG3L2.

Description

This antibody is purified through a protein A column, followed by peptide affinity purification.

Reactivity

Human

Host

Rabbit

Epitope

N-Term,AA 52-80

Antibody clone number

RB33011

Vial size

400 μL

Concentration

0.5 mg/mL

References

Submitted references

Early onset and slow progression of SCA28, a rare dominant ataxia in a large four-generation family with a novel AFG3L2 mutation.

Edener U, Wöllner J, Hehr U, Kohl Z, Schilling S, Kreuz F, Bauer P, Bernard V, Gillessen-Kaesbach G, Zühlke C
European journal of human genetics : EJHG 2010 Aug;18(8):965-8

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Mutations in the mitochondrial protease gene AFG3L2 cause dominant hereditary ataxia SCA28.

Di Bella D, Lazzaro F, Brusco A, Plumari M, Battaglia G, Pastore A, Finardi A, Cagnoli C, Tempia F, Frontali M, Veneziano L, Sacco T, Boda E, Brussino A, Bonn F, Castellotti B, Baratta S, Mariotti C, Gellera C, Fracasso V, Magri S, Langer T, Plevani P, Di Donato S, Muzi-Falconi M, Taroni F
Nature genetics 2010 Apr;42(4):313-21

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An intersubunit signaling network coordinates ATP hydrolysis by m-AAA proteases.

Augustin S, Gerdes F, Lee S, Tsai FT, Langer T, Tatsuta T
Molecular cell 2009 Sep 11;35(5):574-85