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- References [4]
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- Validations
- Western blot [1]
- Immunohistochemistry [2]
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- Product number
- 21186-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#21186-1-AP, RRID:AB_10733125
- Product name
- KIF5A antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated KIF5A antibody (Cat. #21186-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Normal levels of KIF5 but reduced KLC1 levels in both Alzheimer disease and Alzheimer disease in Down syndrome: evidence suggesting defects in anterograde transport.
Mitochondrial transport mediates survival of retinal ganglion cells in affected LHON patients.
Amyloid beta-mediated KIF5A deficiency disrupts anterograde axonal mitochondrial movement.
Axonal transport in a peripheral diabetic neuropathy model: sex-dimorphic features.
Chen XQ, Das U, Park G, Mobley WC
Alzheimer's research & therapy 2021 Mar 10;13(1):59
Alzheimer's research & therapy 2021 Mar 10;13(1):59
Mitochondrial transport mediates survival of retinal ganglion cells in affected LHON patients.
Yang TC, Yarmishyn AA, Yang YP, Lu PC, Chou SJ, Wang ML, Lin TC, Hwang DK, Chou YB, Chen SJ, Yu WK, Wang AG, Hsu CC, Chiou SH
Human molecular genetics 2020 Jun 3;29(9):1454-1464
Human molecular genetics 2020 Jun 3;29(9):1454-1464
Amyloid beta-mediated KIF5A deficiency disrupts anterograde axonal mitochondrial movement.
Wang Q, Tian J, Chen H, Du H, Guo L
Neurobiology of disease 2019 Jul;127:410-418
Neurobiology of disease 2019 Jul;127:410-418
Axonal transport in a peripheral diabetic neuropathy model: sex-dimorphic features.
Pesaresi M, Giatti S, Spezzano R, Romano S, Diviccaro S, Borsello T, Mitro N, Caruso D, Garcia-Segura LM, Melcangi RC
Biology of sex differences 2018 Jan 19;9(1):6
Biology of sex differences 2018 Jan 19;9(1):6
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse brain tissue were subjected to SDS PAGE followed by western blot with 21186-1-AP(KIF5A antibody) at dilution of 1:2000
- Sample type
- tissue
Supportive validation
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The KIF5A antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human KIF5A. This antibody recognizes human, mouse, rat antigen. The KIF5A antibody has been validated for the following applications: ELISA, WB, IHC analysis.
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human brain using 21186-1-AP(KIF5A antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
