PAB13439

antibody from Abnova Corporation

Targeting: CERS5 FLJ25304, LASS5, MGC45411, Trh4

Western blot (Supportive data in Antibodypedia)

Immunocytochemistry (Supportive data in Antibodypedia)

Antibody Data

Product number

PAB13439

Provider

Abnova Corporation

Proper citation

Abnova Corporation Cat#PAB13439, RRID:AB_10555321

Product name

LASS5 polyclonal antibody

Antibody type

Polyclonal

Description

Rabbit polyclonal antibody raised against synthetic peptide of LASS5.

Storage

Store at 4°C for three months. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.

References

Submitted references

Necessary role for the Lag1p motif in (dihydro)ceramide synthase activity.

Spassieva S, Seo JG, Jiang JC, Bielawski J, Alvarez-Vasquez F, Jazwinski SM, Hannun YA, Obeid LM
The Journal of biological chemistry 2006 Nov 10;281(45):33931-8

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LASS5 is a bona fide dihydroceramide synthase that selectively utilizes palmitoyl-CoA as acyl donor.

Lahiri S, Futerman AH
The Journal of biological chemistry 2005 Oct 7;280(40):33735-8

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Two mammalian longevity assurance gene (LAG1) family members, trh1 and trh4, regulate dihydroceramide synthesis using different fatty acyl-CoA donors.

Riebeling C, Allegood JC, Wang E, Merrill AH Jr, Futerman AH
The Journal of biological chemistry 2003 Oct 31;278(44):43452-9

Western blot

Supportive validation

Submitted by

Abnova Corporation (provider)

Main image

Experimental details

Western blot analysis of LASS5 in SK-N-SH lysate with LASS5 polyclonal antibody (Cat # PAB13439) at 1 ug/mL in the (A) absence and (B) presence of blocking peptide.

Immunocytochemistry

Supportive validation

Submitted by

Abnova Corporation (provider)

Main image

Experimental details

Immunofluorescence staining of human brain tissue with 20 ug/mL LASS5 polyclonal antibody (Cat # PAB13439).

Validation comment

Immunofluorescence