H00057447-M03

antibody from Novus Biologicals

Targeting: NDRG2 KIAA1248, SYLD

Provider product page for H00057447-M03

Western blot

ELISA

Immunocytochemistry

Immunohistochemistry

Antibody data

Antibody Data
Antigen structure
References [18]
Comments [0]
Validations
Western blot [2]
ELISA [1]

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Product number: H00057447-M03 - Provider product page
Provider: Novus Biologicals
Proper citation: Novus Cat#H00057447-M03, RRID:AB_2282574
Product name: Mouse Monoclonal NDRG2 Antibody
Antibody type: Monoclonal
Description: IgG purified. NDRG2 - NDRG family member 2
Reactivity: Human
Host: Mouse
Isotype: IgG
Vial size: 0.1 mg
Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

NDRG2 protein structure - H00057447-M03 shown in red.

Submitted references Spatiotemporal expression of NDRG2 in the human fetal brain.

Jin PP, Xia F, Ma BF, Li Z, Zhang GF, Deng YC, Tu ZL, Zhang XX, Hou SX
Annals of anatomy = Anatomischer Anzeiger : official organ of the Anatomische Gesellschaft 2019 Jan;221:148-155

NDRG2 facilitates colorectal cancer differentiation through the regulation of Skp2-p21/p27 axis.

Shen L, Qu X, Li H, Xu C, Wei M, Wang Q, Ru Y, Liu B, Xu Y, Li K, Hu J, Wang L, Ma Y, Li M, Lai X, Gao L, Wu K, Yao L, Zheng J, Zhang J
Oncogene 2018 Mar;37(13):1759-1774

N-myc downstream-regulated gene 2 expression is associated with glucose transport and correlated with prognosis in breast carcinoma.

Ma J, Liu W, Guo H, Li S, Cao W, Du X, Lei S, Hou W, Xiong L, Yao L, Li N, Li Y
Breast cancer research : BCR 2014 Mar 18;16(2):R27

Tumor suppressor NDRG2 tips the balance of oncogenic TGF-β via EMT inhibition in colorectal cancer.

Shen L, Qu X, Ma Y, Zheng J, Chu D, Liu B, Li X, Wang M, Xu C, Liu N, Yao L, Zhang J
Oncogenesis 2014 Feb 3;3(2):e86

NDRG2 is a novel p53-associated regulator of apoptosis in C6-originated astrocytes exposed to oxygen-glucose deprivation.

Li Y, Xu N, Cai L, Gao Z, Shen L, Zhang Q, Hou W, Zhong H, Wang Q, Xiong L
PloS one 2013;8(2):e57130

NDRG2: a newly identified mediator of insulin cardioprotection against myocardial ischemia-reperfusion injury.

Sun Z, Tong G, Ma N, Li J, Li X, Li S, Zhou J, Xiong L, Cao F, Yao L, Wang H, Shen L
Basic research in cardiology 2013 May;108(3):341

Regulation of N-Myc downstream regulated gene 2 by bile acids.

Langhi C, Pedraz-Cuesta E, Donate Y, Marrero PF, Haro D, Rodríguez JC
Biochemical and biophysical research communications 2013 Apr 26;434(1):102-9

NDRG2 down-regulation and CD24 up-regulation promote tumor aggravation and poor survival in patients with gallbladder carcinoma.

Song SP, Zhang SB, Liu R, Yao L, Hao YQ, Liao MM, Zhang YD, Li ZH
Medical oncology (Northwood, London, England) 2012 Sep;29(3):1879-85

Oh SS, Kim D, Kim DH, Chang HH, Sohn KC, Kim KH, Jung SH, Lee BK, Kim JH, Kim KD
Carcinogenesis 2012 Oct;33(10):1882-8

Microarray profiling of HepG2 cells ectopically expressing NDRG2.

Liu X, Niu T, Liu X, Hou W, Zhang J, Yao L
Gene 2012 Jul 15;503(1):48-55

Up-regulation of NDRG2 through nuclear factor-kappa B is required for Leydig cell apoptosis in both human and murine infertile testes.

Li T, Hu J, He GH, Li Y, Zhu CC, Hou WG, Zhang S, Li W, Zhang JS, Wang Z, Liu XP, Yao LB, Zhang YQ
Biochimica et biophysica acta 2012 Feb;1822(2):301-13

Regulation of histone acetylation by NDRG2 in glioma cells.

Li L, Qin X, Shi M, Miao R, Wang L, Liu X, Yao L, Deng Y
Journal of neuro-oncology 2012 Feb;106(3):485-92

NDRG2 ameliorates hepatic fibrosis by inhibiting the TGF-β1/Smad pathway and altering the MMP2/TIMP2 ratio in rats.

Yang J, Zheng J, Wu L, Shi M, Zhang H, Wang X, Xia N, Wang D, Liu X, Yao L, Li Y, Dou K
PloS one 2011;6(11):e27710

Spatial-temporal expression of NDRG2 in rat brain after focal cerebral ischemia and reperfusion.

Li Y, Shen L, Cai L, Wang Q, Hou W, Wang F, Zeng Y, Zhao G, Yao L, Xiong L
Brain research 2011 Mar 25;1382:252-8

NDRG2 inhibits hepatocellular carcinoma adhesion, migration and invasion by regulating CD24 expression.

Zheng J, Li Y, Yang J, Liu Q, Shi M, Zhang R, Shi H, Ren Q, Ma J, Guo H, Tao Y, Xue Y, Jiang N, Yao L, Liu W
BMC cancer 2011 Jun 16;11:251:1-9

Variation of NDRG2 and c-Myc expression in rat heart during the acute stage of ischemia/reperfusion injury.

Sun Z, Shen L, Sun X, Tong G, Sun D, Han T, Yang G, Zhang J, Cao F, Yao L, Wang H
Histochemistry and cell biology 2011 Jan;135(1):27-35

NDRG2 is highly expressed in pancreatic beta cells and involved in protection against lipotoxicity.

Shen L, Liu X, Hou W, Yang G, Wu Y, Zhang R, Li X, Che H, Lu Z, Zhang Y, Liu X, Yao L
Cellular and molecular life sciences : CMLS 2010 Apr;67(8):1371-81

Immunohistochemical detection of Ndrg2 in the mouse nervous system.

Shen L, Zhao ZY, Wang YZ, Ji SP, Liu XP, Liu XW, Che HL, Lin W, Li X, Zhang J, Yao LB
Neuroreport 2008 Jun 11;19(9):927-31

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Supportive validation

Submitted by: Novus Biologicals (provider)
Main image
Experimental details: Western Blot: NDRG2 Antibody (6A5) [H00057447-M03] - Analysis of NDRG2 expression in transfected 293T cell line by NDRG2 monoclonal antibody (M03), clone 6A5. Lane 1: NDRG2 transfected lysatE (39.7 KDa). Lane 2: Non-transfected lysate.

Supportive validation

Submitted by: Novus Biologicals (provider)
Main image
Experimental details: Western Blot: NDRG2 Antibody (6A5) [H00057447-M03] - Analysis of NDRG2 expression in Hela S3 NE.

Supportive validation

Submitted by: Novus Biologicals (provider)
Main image
Experimental details: ELISA: NDRG2 Antibody (6A5) [H00057447-M03] - Detection limit for recombinant GST tagged NDRG2 is approximately 0.03ng/ml as a capture antibody.