MAB2488

antibody from R&D Systems

Targeting: SERPING1 C1-INH, C1IN, C1INH, C1NH, HAE1, HAE2

Western blot (Supportive data in Antibodypedia)

Immunoprecipitation (Data presented on provider website)

Antibody Data

Product number

MAB2488

Provider

R&D Systems

Product name

Human Serpin G1/C1 Inhibitor Antibody

Antibody type

Monoclonal

Description

Protein A or G purified from hybridoma culture supernatant. Detects human Serpin G1/C1 Inhibitor in direct ELISAs and Western blots. In Western blots, no cross-reactivity with recombinant human Serpin A1, A3, A4, A5, C1, D1, E2, or F1 is observed.

Reactivity

Human

Host

Mouse

Conjugate

Unconjugated

Isotype

IgG

Antibody clone number

350507

Vial size

100 ug

Concentration

LYOPH

Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.

References

Submitted references

Extracellular Vesicle Proteins Associated with Systemic Vascular Events Correlate with Heart Failure: An Observational Study in a Dyspnoea Cohort.

Zhang YN, Vernooij F, Ibrahim I, Ooi S, Gijsberts CM, Schoneveld AH, Sen KW, den Ruijter HM, Timmers L, Richards AM, Jong CT, Mazlan I, Wang JW, Lam CS, de Kleijn DP
PloS one 2016;11(1):e0148073

Western blot

Supportive validation

Submitted by

R&D Systems (provider)

Main image

Experimental details

Detection of Serpin G1/C1 Inhibitor by Western Blot. Western blot shows lysates of human lung tissue and human ovary tissue. PVDF membrane was probed with 1 µg/mL of Mouse Anti-Human Serpin G1/C1 Inhibitor Monoclonal Antibody (Catalog # MAB2488) followed by HRP-conjugated Anti-Mouse IgG Secondary Antibody (Catalog # HAF018). A specific band was detected for Serpin G1/C1 Inhibitor at approximately 100 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1.