ABIN500034
antibody from antibodies-online
Targeting: NLRC4
CARD12, CLAN, CLAN1, CLANA, CLANB, CLANC, CLAND, CLR2.1, ipaf
Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
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Validation data
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- Product number
- ABIN500034 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-NLR Family, CARD Domain Containing 4 (NLRC4) antibody
- Antibody type
- Polyclonal
- Antigen
- Human Ipaf / CARD12 / CLANA Peptide (AP30437CP-N)
- Description
- Affinity chromatography purified via peptide column
- Reactivity
- Human
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 0.1 mg
- Storage
- Store the antibody undiluted at 2-8°C.
Submitted references Human CARD12 is a novel CED4/Apaf-1 family member that induces apoptosis.
Identification of Ipaf, a human caspase-1-activating protein related to Apaf-1.
Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade.
Geddes BJ, Wang L, Huang WJ, Lavellee M, Manji GA, Brown M, Jurman M, Cao J, Morgenstern J, Merriam S, Glucksmann MA, DiStefano PS, Bertin J
Biochemical and biophysical research communications 2001 Jun 1;284(1):77-82
Biochemical and biophysical research communications 2001 Jun 1;284(1):77-82
Identification of Ipaf, a human caspase-1-activating protein related to Apaf-1.
Poyet JL, Srinivasula SM, Tnani M, Razmara M, Fernandes-Alnemri T, Alnemri ES
The Journal of biological chemistry 2001 Jul 27;276(30):28309-13
The Journal of biological chemistry 2001 Jul 27;276(30):28309-13
Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade.
Li P, Nijhawan D, Budihardjo I, Srinivasula SM, Ahmad M, Alnemri ES, Wang X
Cell 1997 Nov 14;91(4):479-89
Cell 1997 Nov 14;91(4):479-89
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Western blot analysis of Ipaf in human PBL lysate with AP30437PU-N Ipaf antibody at 0.5 (lane A), 1 (lane B), and 2 (lane C) ?g/ml, respectively.
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Immunocytochemistry of Ipaf in THP-1 cells with AP30437PU-N Ipaf antibody at 10 ?g/ml.