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Protein structure
CYP46A1
Cytochrome P450 family 46 subfamily A member 1CYP46
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein is expressed in the brain, where it converts cholesterol to 24S-hydroxycholesterol. While cholesterol cannot pass the blood-brain barrier, 24S-hydroxycholesterol can be secreted in the brain into the circulation to be returned to the liver for catabolism. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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| Proteintech Group |  12486-1-AP |
5 references | Polyclonal |
WB
EL
IP
IHC
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| Invitrogen Antibodies | 12486-1-AP |
Polyclonal |
WB
IP
IHC
OA
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| Novus Biologicals | NB400-140 |
2 references | Polyclonal |
WB
ICC
IHC
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| antibodies-online | ABIN2030048 |
Polyclonal |
WB
EL
IHC
FC
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| NovoPro Bioscience Inc. | 109702 |
Polyclonal |
WB
EL
IP
IHC
|
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