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Protein structure
IBSP
Integrin binding sialoproteinBSP, BSP-II, SP-II
The protein encoded by this gene is a major structural protein of the bone matrix. It constitutes approximately 12% of the noncollagenous proteins in human bone and is synthesized by skeletal-associated cell types, including hypertrophic chondrocytes, osteoblasts, osteocytes, and osteoclasts. The only extraskeletal site of its synthesis is the trophoblast. This protein binds to calcium and hydroxyapatite via its acidic amino acid clusters, and mediates cell attachment through an RGD sequence that recognizes the vitronectin receptor. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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| antibodies-online |  ABIN191976 |
8 references | Monoclonal |
WB
ICC
IHC
FC
RA
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| OriGene | AP02055PU-N |
Polyclonal |
WB
EL
ICC
IHC
FC
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| Invitrogen Antibodies | PA5-50633 |
1 references | Polyclonal |
WB
IHC
OA
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| Acris Antibodies GmbH | AM02057PU-N |
Monoclonal |
WB
EL
ICC
IHC
RA
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| GeneTex | GTX44333 |
Polyclonal |
WB
EL
IHC
RA
|
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