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Protein structure
IL13
Interleukin 13ALRH, BHR1, IL-13, MGC116786, MGC116788, MGC116789, P600
This gene encodes an immunoregulatory cytokine produced primarily by activated Th2 cells. This cytokine is involved in several stages of B-cell maturation and differentiation. It up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. This cytokine down-regulates macrophage activity, thereby inhibits the production of pro-inflammatory cytokines and chemokines. This cytokine is found to be critical to the pathogenesis of allergen-induced asthma but operates through mechanisms independent of IgE and eosinophils. This gene, IL3, IL5, IL4, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL4. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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| R&D Systems |  AF-413-NA |
12 references | Polyclonal |
WB
ICC
BN
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| Invitrogen Antibodies | AHC0132 |
4 references | Monoclonal |
WB
EL
IHC
FC
BN
OA
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| antibodies-online | ABIN2487875 |
Monoclonal |
WB
EL
ICC
IHC
FC
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| Novus Biologicals | AF-413-NA |
12 references | Polyclonal |
WB
ICC
BN
|
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| NovoPro Bioscience Inc. | 136869 |
Polyclonal |
WB
EL
ICC
IHC
|
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