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antibody from Invitrogen Antibodies
Targeting: IL13
ALRH, BHR1, IL-13, MGC116786, MGC116788, MGC116789, P600
ELISAAntibody data
- Antibody Data
- Antigen structure
- References [4]
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- Validations
- ELISA [1]
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- Product number
- 14-7139-81 - Provider product page
- Provider
- Invitrogen Antibodies
- Product name
- IL-13 Monoclonal Antibody (PVM13-1), eBioscience™
- Antibody type
- Monoclonal
- Antigen
- Other
- Description
- Description: The PVM13-1 antibody reacts with human interleukin-13 (IL-13). IL-13, also known as NC30, is a 12.5 kDa protein secreted by activated T helper cells, CD8^+ T cells, and NK cells. The biological activities of IL-13 include suppression of macrophage cytotoxic activity, upregulation of IL-1RA expression and suppression of inflammatory cytokine expression.
- Antibody clone number
- PVM13-1
- Concentration
- 0.5 mg/mL
Submitted references A molecular signature of preclinical rheumatoid arthritis triggered by dysregulated PTPN22.
COPA mutations impair ER-Golgi transport and cause hereditary autoimmune-mediated lung disease and arthritis.
Protein microarray analysis reveals BAFF-binding autoantibodies in systemic lupus erythematosus.
Comparison of cytokine ELISpot assay formats for the detection of islet antigen autoreactive T cells. Report of the third immunology of diabetes society T-cell workshop.
Chang HH, Liu GY, Dwivedi N, Sun B, Okamoto Y, Kinslow JD, Deane KD, Demoruelle MK, Norris JM, Thompson PR, Sparks JA, Rao DA, Karlson EW, Hung HC, Holers VM, Ho IC
JCI insight 2016 Oct 20;1(17):e90045
JCI insight 2016 Oct 20;1(17):e90045
COPA mutations impair ER-Golgi transport and cause hereditary autoimmune-mediated lung disease and arthritis.
Watkin LB, Jessen B, Wiszniewski W, Vece TJ, Jan M, Sha Y, Thamsen M, Santos-Cortez RL, Lee K, Gambin T, Forbes LR, Law CS, Stray-Pedersen A, Cheng MH, Mace EM, Anderson MS, Liu D, Tang LF, Nicholas SK, Nahmod K, Makedonas G, Canter DL, Kwok PY, Hicks J, Jones KD, Penney S, Jhangiani SN, Rosenblum MD, Dell SD, Waterfield MR, Papa FR, Muzny DM, Zaitlen N, Leal SM, Gonzaga-Jauregui C, Baylor-Hopkins Center for Mendelian Genomics, Boerwinkle E, Eissa NT, Gibbs RA, Lupski JR, Orange JS, Shum AK
Nature genetics 2015 Jun;47(6):654-60
Nature genetics 2015 Jun;47(6):654-60
Protein microarray analysis reveals BAFF-binding autoantibodies in systemic lupus erythematosus.
Price JV, Haddon DJ, Kemmer D, Delepine G, Mandelbaum G, Jarrell JA, Gupta R, Balboni I, Chakravarty EF, Sokolove J, Shum AK, Anderson MS, Cheng MH, Robinson WH, Browne SK, Holland SM, Baechler EC, Utz PJ
The Journal of clinical investigation 2013 Dec;123(12):5135-45
The Journal of clinical investigation 2013 Dec;123(12):5135-45
Comparison of cytokine ELISpot assay formats for the detection of islet antigen autoreactive T cells. Report of the third immunology of diabetes society T-cell workshop.
Schloot NC, Meierhoff G, Karlsson Faresjö M, Ott P, Putnam A, Lehmann P, Gottlieb P, Roep BO, Peakman M, Tree T
Journal of autoimmunity 2003 Dec;21(4):365-76
Journal of autoimmunity 2003 Dec;21(4):365-76
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Supportive validation
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- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Human PBMCs (300,000/well) in 100 µL complete RPMI medium were treated without (left) or with (right) Candida (100 µg/mL) for 24 hrs in an IL-13 ELISPOT assay.
