MUC7

This gene encodes a small salivary mucin, which is thought to play a role in facilitating the clearance of bacteria in the oral cavity and to aid in mastication, speech, and swallowing. The central domain of this glycoprotein contains tandem repeats, each composed of 23 amino acids. This antimicrobial protein has antibacterial and antifungal activity. The most common allele contains 6 repeats, and some alleles may be associated with susceptibility to asthma. Alternatively spliced transcript variants with different 5' UTR, but encoding the same protein, have been found for this gene. [provided by RefSeq, Oct 2014]

Description

Mucin 7, secreted

Tissue specificity

Tissue enriched (salivary gland)

Predicted location

Secreted to digestive system

Protein family

Disease related genes
Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted secreted proteins
Protein evidence (Ezkurdia et al 2014)
Protein evidence (Kim et al 2014)

Chromosome

4 (70430492 - 70482997)

Ensembl ID

ENSG00000171195  (ver. 103.38)

Orthologs

-

UniProt

Q8TAX7

neXtProt

NX_Q8TAX7

Human splice variants

Protein structure