Explore
Validate
Learn
Western blot
ImmunohistochemistryAntibody data
- Antibody Data
- Antigen structure
- References [12]
- Comments [0]
- Validations
- Immunohistochemistry [1]
Submit
Validation data
Reference
Comment
Report error
- Product number
- NBP1-00121 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#NBP1-00121, RRID:AB_1503594
- Product name
- Rabbit Polyclonal MafA Antibody
- Antibody type
- Polyclonal
- Description
- Immunogen affinity purified.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 0.1 ml
- Concentration
- 1.0 mg/ml
- Storage
- Store at 4C. Do not freeze.
Submitted references Sel1L-Hrd1 ER-associated degradation maintains β cell identity via TGF-β signaling.
The Pdx1-Bound Swi/Snf Chromatin Remodeling Complex Regulates Pancreatic Progenitor Cell Proliferation and Mature Islet β-Cell Function.
mTORC1 to AMPK switching underlies β-cell metabolic plasticity during maturation and diabetes.
LIM-domain transcription complexes interact with ring-finger ubiquitin ligases and thereby impact islet β-cell function.
B lymphocytes protect islet β cells in diabetes prone NOD mice treated with imatinib.
Defining a Novel Role for the Pdx1 Transcription Factor in Islet β-Cell Maturation and Proliferation During Weaning.
The MAFB transcription factor impacts islet α-cell function in rodents and represents a unique signature of primate islet β-cells.
MLL3 and MLL4 Methyltransferases Bind to the MAFA and MAFB Transcription Factors to Regulate Islet β-Cell Function.
Characterization of age-associated alterations of islet function and structure in diabetic mutant cryptochrome 1 transgenic mice.
Two distinct origins for Leydig cell progenitors in the fetal testis.
Islet beta-cell-specific MafA transcription requires the 5'-flanking conserved region 3 control domain.
Insulin transactivator MafA regulates intrathymic expression of insulin and affects susceptibility to type 1 diabetes.
Shrestha N, Liu T, Ji Y, Reinert RB, Torres M, Li X, Zhang M, Tang CA, Hu CA, Liu C, Naji A, Liu M, Lin JD, Kersten S, Arvan P, Qi L
The Journal of clinical investigation 2020 Jul 1;130(7):3499-3510
The Journal of clinical investigation 2020 Jul 1;130(7):3499-3510
The Pdx1-Bound Swi/Snf Chromatin Remodeling Complex Regulates Pancreatic Progenitor Cell Proliferation and Mature Islet β-Cell Function.
Spaeth JM, Liu JH, Peters D, Guo M, Osipovich AB, Mohammadi F, Roy N, Bhushan A, Magnuson MA, Hebrok M, Wright CVE, Stein R
Diabetes 2019 Sep;68(9):1806-1818
Diabetes 2019 Sep;68(9):1806-1818
mTORC1 to AMPK switching underlies β-cell metabolic plasticity during maturation and diabetes.
Jaafar R, Tran S, Shah AN, Sun G, Valdearcos M, Marchetti P, Masini M, Swisa A, Giacometti S, Bernal-Mizrachi E, Matveyenko A, Hebrok M, Dor Y, Rutter GA, Koliwad SK, Bhushan A
The Journal of clinical investigation 2019 Jul 2;129(10):4124-4137
The Journal of clinical investigation 2019 Jul 2;129(10):4124-4137
LIM-domain transcription complexes interact with ring-finger ubiquitin ligases and thereby impact islet β-cell function.
Wade AK, Liu Y, Bethea MM, Toren E, Tse HM, Hunter CS
The Journal of biological chemistry 2019 Aug 2;294(31):11728-11740
The Journal of biological chemistry 2019 Aug 2;294(31):11728-11740
B lymphocytes protect islet β cells in diabetes prone NOD mice treated with imatinib.
Wilson CS, Spaeth JM, Karp J, Stocks BT, Hoopes EM, Stein RW, Moore DJ
JCI insight 2019 Apr 9;5(9)
JCI insight 2019 Apr 9;5(9)
Defining a Novel Role for the Pdx1 Transcription Factor in Islet β-Cell Maturation and Proliferation During Weaning.
Spaeth JM, Gupte M, Perelis M, Yang YP, Cyphert H, Guo S, Liu JH, Guo M, Bass J, Magnuson MA, Wright C, Stein R
Diabetes 2017 Nov;66(11):2830-2839
Diabetes 2017 Nov;66(11):2830-2839
The MAFB transcription factor impacts islet α-cell function in rodents and represents a unique signature of primate islet β-cells.
Conrad E, Dai C, Spaeth J, Guo M, Cyphert HA, Scoville D, Carroll J, Yu WM, Goodrich LV, Harlan DM, Grove KL, Roberts CT Jr, Powers AC, Gu G, Stein R
American journal of physiology. Endocrinology and metabolism 2016 Jan 1;310(1):E91-E102
American journal of physiology. Endocrinology and metabolism 2016 Jan 1;310(1):E91-E102
MLL3 and MLL4 Methyltransferases Bind to the MAFA and MAFB Transcription Factors to Regulate Islet β-Cell Function.
Scoville DW, Cyphert HA, Liao L, Xu J, Reynolds A, Guo S, Stein R
Diabetes 2015 Nov;64(11):3772-83
Diabetes 2015 Nov;64(11):3772-83
Characterization of age-associated alterations of islet function and structure in diabetic mutant cryptochrome 1 transgenic mice.
Okano S, Hayasaka K, Igarashi M, Togashi Y, Nakajima O
Journal of diabetes investigation 2013 Sep 13;4(5):428-35
Journal of diabetes investigation 2013 Sep 13;4(5):428-35
Two distinct origins for Leydig cell progenitors in the fetal testis.
DeFalco T, Takahashi S, Capel B
Developmental biology 2011 Apr 1;352(1):14-26
Developmental biology 2011 Apr 1;352(1):14-26
Islet beta-cell-specific MafA transcription requires the 5'-flanking conserved region 3 control domain.
Raum JC, Hunter CS, Artner I, Henderson E, Guo M, Elghazi L, Sosa-Pineda B, Ogihara T, Mirmira RG, Sussel L, Stein R
Molecular and cellular biology 2010 Sep;30(17):4234-44
Molecular and cellular biology 2010 Sep;30(17):4234-44
Insulin transactivator MafA regulates intrathymic expression of insulin and affects susceptibility to type 1 diabetes.
Noso S, Kataoka K, Kawabata Y, Babaya N, Hiromine Y, Yamaji K, Fujisawa T, Aramata S, Kudo T, Takahashi S, Ikegami H
Diabetes 2010 Oct;59(10):2579-87
Diabetes 2010 Oct;59(10):2579-87
No comments: Submit comment
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: MafA Antibody [NBP1-00121] - Section of mouse pancreatic islet. Antibody: Affinity purified rabbit anti-MafA (Cat. No. NBP1-00121) used at a dilution of 1:250.
