BS1596

antibody from Bioworld Technology, Inc

Targeting: SNCA NACP, PARK1, PARK4, PD1

Immunohistochemistry

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Validation data

Product number: BS1596 - Provider product page
Provider: Bioworld Technology, Inc
Proper citation: Bioworld Technology Cat#BS1596, RRID:AB_1663273
Product name: Synuclein Ï« (E123) polyclonal antibody
Antibody type: Polyclonal
Antigen: Synthetic peptide, corresponding to amino acids 100-150 of Human Synuclein-Ï«.
Description: The synuclein family members, including Ï«-synuclein (also designated NACP for non-ÉÇ amyloid component) and ÉÇ-synuclein, are predominantly expressed in the brain and are speculated to be involved in synaptic regulation and neuronal plasticity. Ï«-synuclein is localized to neuronal cell bodies and synapses. Ï«-synuclein was first identified as a component of Alzheimer£ªs disease amyloid plaques. Abnormal platelet function in Alzheimer£ªs disease has been demonstrated. During megakaryocytic differentiation Ï«-synuclein was found to be up-regulated, while ÉÇ-synuclein is down-regulated, indicating that coordinate expression of synucleins may be important during hematopoetic cell differentiation. A mutant form of Ï«-synuclein has been found in patients with early onset Parkinson£ªs disease.
Reactivity: Human, Mouse, Rat
Host: Rabbit
Isotype: IgG
Vial size: 100ul
Concentration: 1 mg/ml
Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SNCA protein structure - BS1596 shown in red.