ADH6

This gene encodes class V alcohol dehydrogenase, which is a member of the alcohol dehydrogenase family. Members of this family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. This gene is expressed in the stomach as well as in the liver, and it contains a glucocorticoid response element upstream of its 5' UTR, which is a steroid hormone receptor binding site. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Description

Alcohol dehydrogenase 6 (class V)

Tissue specificity

Tissue enriched (liver)

Predicted location

Intracellular

Protein family

Enzymes
Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Metabolic proteins
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Protein evidence (Kim et al 2014)

Chromosome

4 (99202638 - 99219537)

Ensembl ID

ENSG00000172955  (ver. 103.38)

Orthologs

Mouse Adh6b: ENSMUSG00000074206

UniProt

P28332

neXtProt

NX_P28332

Human splice variants
Mouse splice variants

Protein structure