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- References [5]
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- Product number
- ABIN396608 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Neural Wiskott-Aldrich syndrome protein (WASL) (AA 97-185) antibody
- Antibody type
- Monoclonal
- Description
- This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
- Reactivity
- Human
- Host
- Mouse
- Epitope
- AA 97-185
- Isotype
- IgG
- Antibody clone number
- 5F4
- Vial size
- 100 μg
- Storage
- Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Submitted references Regulation of actin polymerization and adhesion-dependent cell edge protrusion by the Abl-related gene (Arg) tyrosine kinase and N-WASp.
The rate of N-WASP exchange limits the extent of ARP2/3-complex-dependent actin-based motility.
The Toca-1-N-WASP complex links filopodial formation to endocytosis.
Overexpression of N-WASP in the brain of human epilepsy.
Inhibition of cytokinesis by wiskostatin does not rely on N-WASP/Arp2/3 complex pathway.
Miller MM, Lapetina S, MacGrath SM, Sfakianos MK, Pollard TD, Koleske AJ
Biochemistry 2010 Mar 16;49(10):2227-34
Biochemistry 2010 Mar 16;49(10):2227-34
The rate of N-WASP exchange limits the extent of ARP2/3-complex-dependent actin-based motility.
Weisswange I, Newsome TP, Schleich S, Way M
Nature 2009 Mar 5;458(7234):87-91
Nature 2009 Mar 5;458(7234):87-91
The Toca-1-N-WASP complex links filopodial formation to endocytosis.
Bu W, Chou AM, Lim KB, Sudhaharan T, Ahmed S
The Journal of biological chemistry 2009 Apr 24;284(17):11622-36
The Journal of biological chemistry 2009 Apr 24;284(17):11622-36
Overexpression of N-WASP in the brain of human epilepsy.
Xiao F, Wang XF, Li JM, Xi ZQ, Lu Y, Wang L, Zeng Y, Guan LF, Yuan J
Brain research 2008 Oct 3;1233:168-75
Brain research 2008 Oct 3;1233:168-75
Inhibition of cytokinesis by wiskostatin does not rely on N-WASP/Arp2/3 complex pathway.
Bompard G, Rabeharivelo G, Morin N
BMC cell biology 2008 Jul 30;9:42
BMC cell biology 2008 Jul 30;9:42
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Supportive validation
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