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- References [22]
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- Western blot [2]
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- Product number
- 24324-1-AP - Provider product page
- Provider
- Proteintech Group
- Product name
- Sodium iodide symporter antibody
- Antibody type
- Polyclonal
- Description
- Sodium iodide symporter antibody (Cat. #24324-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: FC, IHC, IP, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Downregulation of Rap1GAP Expression Activates the TGF-β/Smad3 Pathway to Inhibit the Expression of Sodium/Iodine Transporter in Papillary Thyroid Carcinoma Cells.
XBP1s Acts as a Tumor Suppressor to Inhibit the EMT Process and Metastasis of Papillary Thyroid Cancer.
Targeting non-canonical pathways as a strategy to modulate the sodium iodide symporter.
MAPK Inhibition Requires Active RAC1 Signaling to Effectively Improve Iodide Uptake by Thyroid Follicular Cells.
PKCα mediated by the PI3K/Akt-FOXA1 cascade facilitates cypermethrin-induced hyperthyroidism.
CRSP8 promotes thyroid cancer progression by antagonizing IKKα-induced cell differentiation.
TNFα-mediated activation of NF-κB downregulates sodium-iodide symporter expression in thyroid cells.
Patient-Derived Papillary Thyroid Cancer Organoids for Radioactive Iodine Refractory Screening.
Combined tazemetostat and MAPKi enhances differentiation of papillary thyroid cancer cells harbouring BRAFV600E by synergistically decreasing global trimethylation of H3K27.
REGγ ablation impedes dedifferentiation of anaplastic thyroid carcinoma and accentuates radio-therapeutic response by regulating the Smad7-TGF-β pathway.
Human Bone Marrow Mesenchymal Stem Cells Modified Hybrid Baculovirus-Adeno-Associated Viral Vectors Targeting 131I Therapy of Hypopharyngeal Carcinoma.
Dimerization of the Sodium/Iodide Symporter.
Human Bone Marrow Mesenchymal Stem Cells Functionalized by Hybrid Baculovirus-Adeno-Associated Viral Vectors for Targeting Hypopharyngeal Carcinoma.
A somatic mutation of RasGRP3 decreases Na+/I- symporter expression in metastases of radioactive iodine-refractory thyroid cancer by stimulating the Akt signaling pathway.
Synergistic inhibition of MEK/ERK and BRAF V600E with PD98059 and PLX4032 induces sodium/iodide symporter (NIS) expression and radioiodine uptake in BRAF mutated papillary thyroid cancer cells.
HER inhibitor promotes BRAF/MEK inhibitor-induced redifferentiation in papillary thyroid cancer harboring BRAFV600E.
Use of rhenium-188 for in vivo imaging and treatment of human cervical cancer cells transfected with lentivirus expressing sodium iodide symporter.
2,3',4,4',5-Pentachlorobiphenyl Induces Inflammatory Responses in the Thyroid Through JNK and Aryl Hydrocarbon Receptor-Mediated Pathway.
Influx mechanisms in the embryonic and adult rat choroid plexus: a transcriptome study.
In vivo molecular imaging and radionuclide (131I) therapy of human nasopharyngeal carcinoma cells transfected with a lentivirus expressing sodium iodide symporter.
Iodide- and glucose-handling gene expression regulated by sorafenib or cabozantinib in papillary thyroid cancer.
Feasibility of lentiviral‑mediated sodium iodide symporter gene delivery for the efficient monitoring of bone marrow‑derived mesenchymal stem cell transplantation and survival.
Yan Z, Yangyanqiu W, Shuwen H, Jing M, Haihong L, Gong C, Yin J, Qing Z, Weili G
BioMed research international 2021;2021:6840642
BioMed research international 2021;2021:6840642
XBP1s Acts as a Tumor Suppressor to Inhibit the EMT Process and Metastasis of Papillary Thyroid Cancer.
Yang W, Xu X, Xu M, Zhou J, Xi Z, Guo H, Ming J, Huang T
OncoTargets and therapy 2021;14:2339-2348
OncoTargets and therapy 2021;14:2339-2348
Targeting non-canonical pathways as a strategy to modulate the sodium iodide symporter.
Read ML, Brookes K, Thornton CEM, Fletcher A, Nieto HR, Alshahrani M, Khan R, Borges de Souza P, Zha L, Webster JRM, Alderwick LJ, Campbell MJ, Boelaert K, Smith VE, McCabe CJ
Cell chemical biology 2021 Sep 11;
Cell chemical biology 2021 Sep 11;
MAPK Inhibition Requires Active RAC1 Signaling to Effectively Improve Iodide Uptake by Thyroid Follicular Cells.
Faria M, Domingues R, Bugalho MJ, Matos P, Silva AL
Cancers 2021 Nov 22;13(22)
Cancers 2021 Nov 22;13(22)
PKCα mediated by the PI3K/Akt-FOXA1 cascade facilitates cypermethrin-induced hyperthyroidism.
Ha M, Huang X, Li L, Lu D, Liu C
The Science of the total environment 2021 Feb 25;757:143727
The Science of the total environment 2021 Feb 25;757:143727
CRSP8 promotes thyroid cancer progression by antagonizing IKKα-induced cell differentiation.
Liao Y, Hua Y, Li Y, Zhang C, Yu W, Guo P, Zou K, Li W, Sun Y, Wang R, Zuo Y, Sui S, Tian C, Hao J, Chen M, Hu S, Chen M, Long Q, Wang X, Zou L, Xie F, Guo W, Deng W
Cell death and differentiation 2021 Apr;28(4):1347-1363
Cell death and differentiation 2021 Apr;28(4):1347-1363
TNFα-mediated activation of NF-κB downregulates sodium-iodide symporter expression in thyroid cells.
Faria M, Domingues R, Paixão F, Bugalho MJ, Matos P, Silva AL
PloS one 2020;15(2):e0228794
PloS one 2020;15(2):e0228794
Patient-Derived Papillary Thyroid Cancer Organoids for Radioactive Iodine Refractory Screening.
Sondorp LHJ, Ogundipe VML, Groen AH, Kelder W, Kemper A, Links TP, Coppes RP, Kruijff S
Cancers 2020 Oct 31;12(11)
Cancers 2020 Oct 31;12(11)
Combined tazemetostat and MAPKi enhances differentiation of papillary thyroid cancer cells harbouring BRAFV600E by synergistically decreasing global trimethylation of H3K27.
Fu H, Cheng L, Sa R, Jin Y, Chen L
Journal of cellular and molecular medicine 2020 Mar;24(6):3336-3345
Journal of cellular and molecular medicine 2020 Mar;24(6):3336-3345
REGγ ablation impedes dedifferentiation of anaplastic thyroid carcinoma and accentuates radio-therapeutic response by regulating the Smad7-TGF-β pathway.
Jiao C, Li L, Zhang P, Zhang L, Li K, Fang R, Yuan L, Shi K, Pan L, Guo Q, Gao X, Chen G, Xu S, Wang Q, Zuo D, Wu W, Qiao S, Wang X, Moses R, Xiao J, Li L, Dang Y, Li X
Cell death and differentiation 2020 Feb;27(2):497-508
Cell death and differentiation 2020 Feb;27(2):497-508
Human Bone Marrow Mesenchymal Stem Cells Modified Hybrid Baculovirus-Adeno-Associated Viral Vectors Targeting 131I Therapy of Hypopharyngeal Carcinoma.
Wang J, Kong D, Zhu L, Wang S, Sun X
Human gene therapy 2020 Dec;31(23-24):1300-1311
Human gene therapy 2020 Dec;31(23-24):1300-1311
Dimerization of the Sodium/Iodide Symporter.
Thompson RJ, Fletcher A, Brookes K, Nieto H, Alshahrani MM, Mueller JW, Fine NHF, Hodson DJ, Boelaert K, Read ML, Smith VE, McCabe CJ
Thyroid : official journal of the American Thyroid Association 2019 Oct;29(10):1485-1498
Thyroid : official journal of the American Thyroid Association 2019 Oct;29(10):1485-1498
Human Bone Marrow Mesenchymal Stem Cells Functionalized by Hybrid Baculovirus-Adeno-Associated Viral Vectors for Targeting Hypopharyngeal Carcinoma.
Wang J, Zhu L, Chen X, Huang R, Wang S, Dong P
Stem cells and development 2019 Apr 15;28(8):543-553
Stem cells and development 2019 Apr 15;28(8):543-553
A somatic mutation of RasGRP3 decreases Na+/I- symporter expression in metastases of radioactive iodine-refractory thyroid cancer by stimulating the Akt signaling pathway.
Song J, Qiu W, Deng X, Qiu Z, Fan Y, Yang Z
American journal of cancer research 2018;8(9):1847-1855
American journal of cancer research 2018;8(9):1847-1855
Synergistic inhibition of MEK/ERK and BRAF V600E with PD98059 and PLX4032 induces sodium/iodide symporter (NIS) expression and radioiodine uptake in BRAF mutated papillary thyroid cancer cells.
Zhang H, Chen D
Thyroid research 2018;11:13
Thyroid research 2018;11:13
HER inhibitor promotes BRAF/MEK inhibitor-induced redifferentiation in papillary thyroid cancer harboring BRAFV600E.
Cheng L, Jin Y, Liu M, Ruan M, Chen L
Oncotarget 2017 Mar 21;8(12):19843-19854
Oncotarget 2017 Mar 21;8(12):19843-19854
Use of rhenium-188 for in vivo imaging and treatment of human cervical cancer cells transfected with lentivirus expressing sodium iodide symporter.
Zhang M, Shi S, Guo R, Miao Y, Li B
Oncology reports 2016 Oct;36(4):2289-97
Oncology reports 2016 Oct;36(4):2289-97
2,3',4,4',5-Pentachlorobiphenyl Induces Inflammatory Responses in the Thyroid Through JNK and Aryl Hydrocarbon Receptor-Mediated Pathway.
Xu B, Yang H, Sun M, Chen H, Jiang L, Zheng X, Ding G, Liu Y, Sheng Y, Cui D, Duan Y
Toxicological sciences : an official journal of the Society of Toxicology 2016 Feb;149(2):300-11
Toxicological sciences : an official journal of the Society of Toxicology 2016 Feb;149(2):300-11
Influx mechanisms in the embryonic and adult rat choroid plexus: a transcriptome study.
Saunders NR, Dziegielewska KM, Møllgård K, Habgood MD, Wakefield MJ, Lindsay H, Stratzielle N, Ghersi-Egea JF, Liddelow SA
Frontiers in neuroscience 2015;9:123
Frontiers in neuroscience 2015;9:123
In vivo molecular imaging and radionuclide (131I) therapy of human nasopharyngeal carcinoma cells transfected with a lentivirus expressing sodium iodide symporter.
Shi S, Zhang M, Guo R, Miao Y, Hu J, Xi Y, Li B
PloS one 2015;10(1):e0116531
PloS one 2015;10(1):e0116531
Iodide- and glucose-handling gene expression regulated by sorafenib or cabozantinib in papillary thyroid cancer.
Ruan M, Liu M, Dong Q, Chen L
The Journal of clinical endocrinology and metabolism 2015 May;100(5):1771-9
The Journal of clinical endocrinology and metabolism 2015 May;100(5):1771-9
Feasibility of lentiviral‑mediated sodium iodide symporter gene delivery for the efficient monitoring of bone marrow‑derived mesenchymal stem cell transplantation and survival.
Shi S, Zhang M, Guo R, Miao Y, Zhang M, Hu J, Xi Y, Li B
International journal of molecular medicine 2014 Dec;34(6):1547-54
International journal of molecular medicine 2014 Dec;34(6):1547-54
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse stomach tissue were subjected to SDS PAGE followed by western blot with 24324-1-AP( SLC5A5 Antibody) at dilution of 1:600
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse testis tissue were subjected to SDS PAGE followed by western blot with 24324-1-AP( SLC5A5 Antibody) at dilution of 1:600
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The Sodium iodide symporter antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human Sodium iodide symporter. This antibody recognizes human, mouse, rat antigen. The Sodium iodide symporter antibody has been validated for the following applications: ELISA, WB, IHC, FC analysis.
