Tissue expression
Cell line expression
Protein structure
IDH3A
Isocitrate dehydrogenase (NAD(+)) 3 catalytic subunit alphaIsocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. NAD(+)-dependent isocitrate dehydrogenases catalyze the allosterically regulated rate-limiting step of the tricarboxylic acid cycle. Each isozyme is a heterotetramer that is composed of two alpha subunits, one beta subunit, and one gamma subunit. The protein encoded by this gene is the alpha subunit of one isozyme of NAD(+)-dependent isocitrate dehydrogenase. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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Proteintech Group | 15909-1-AP | 14 references | Polyclonal |
WB
EL
ICC
IP
IHC
|
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OriGene | TA500739 | 1 references | Monoclonal |
WB
ICC
IHC
FC |
|
Invitrogen Antibodies | 15909-1-AP | Polyclonal |
WB
ICC
IP
IHC
OA
|
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LSBio | LS-C670518 | Polyclonal |
WB
EL
ICC
IP
IHC
|
||
GeneTex | GTX104073 | 1 references | Polyclonal |
WB
ICC
IHC
|
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Supportive data in Antibodypedia
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Recommended by provider