ABIN4956855

antibody from antibodies-online

Targeting: INA NEF5, NF-66

Western blot (Supportive data in Antibodypedia)

Immunocytochemistry (Data presented on provider website)

Immunohistochemistry (Supportive data in Antibodypedia)

Antibody Data

Product number

ABIN4956855

Provider

antibodies-online

Product name

anti-Internexin Neuronal Intermediate Filament Protein, alpha (INA) antibody

Antibody type

Monoclonal

Description

Tissue culture supernatant

Reactivity

Human, Mouse, Rat, Bovine, Porcine

Host

Mouse

Isotype

IgG

Antibody clone number

2-00E03

Vial size

0.1 mL

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Handling

Avoid freeze-thaw cycles

References

Submitted references

Tumor cells with neuronal intermediate progenitor features define a subgroup of 1p/19q co-deleted anaplastic gliomas.

Bielle F, Ducray F, Mokhtari K, Dehais C, Adle-Biassette H, Carpentier C, Chanut A, Polivka M, Poggioli S, Rosenberg S, Giry M, Marie Y, Duyckaerts C, Sanson M, Figarella-Branger D, Idbaih A, Pola Network.
Brain pathology (Zurich, Switzerland) 2017 Sep;27(5):567-579

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Diffuse gliomas with FGFR3-TACC3 fusion have characteristic histopathological and molecular features.

Bielle F, Di Stefano AL, Meyronet D, Picca A, Villa C, Bernier M, Schmitt Y, Giry M, Rousseau A, Figarella-Branger D, Maurage CA, Uro-Coste E, Lasorella A, Iavarone A, Sanson M, Mokhtari K
Brain pathology (Zurich, Switzerland) 2017 Oct 4;

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BRAF-V600E immunohistochemistry in a large series of glial and glial-neuronal tumors.

Breton Q, Plouhinec H, Prunier-Mirebeau D, Boisselier B, Michalak S, Menei P, Rousseau A
Brain and behavior 2017 Mar;7(3):e00641

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Coexpression of cyclin D1 and alpha-internexin in oligodendroglial tumors.

Matsumura N, Nobusawa S, Ikota H, Hirato J, Hirose T, Yokoo H, Nakazato Y
Brain tumor pathology 2015 Oct;32(4):261-7

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Localized overexpression of alpha-internexin within nodules in multinodular and vacuolating neuronal tumors.

Nagaishi M, Yokoo H, Nobusawa S, Fujii Y, Sugiura Y, Suzuki R, Tanaka Y, Suzuki K, Hyodo A
Neuropathology : official journal of the Japanese Society of Neuropathology 2015 Dec;35(6):561-8

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Mitotic index, microvascular proliferation, and necrosis define 3 groups of 1p/19q codeleted anaplastic oligodendrogliomas associated with different genomic alterations.

Figarella-Branger D, Mokhtari K, Dehais C, Jouvet A, Uro-Coste E, Colin C, Carpentier C, Forest F, Maurage CA, Vignaud JM, Polivka M, Lechapt-Zalcman E, Eimer S, Viennet G, Quintin-Roué I, Aubriot-Lorton MH, Diebold MD, Loussouarn D, Lacroix C, Rigau V, Laquerrière A, Vandenbos F, Michalak S, Sevestre H, Peoch M, Labrousse F, Christov C, Kemeny JL, Chenard MP, Chiforeanu D, Ducray F, Idbaih A, POLA Network.
Neuro-oncology 2014 Sep;16(9):1244-54

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Alpha-internexin and altered CIC expression as a supportive diagnostic marker for oligodendroglial tumors with the 1p/19q co-deletion.

Nagaishi M, Suzuki A, Nobusawa S, Yokoo H, Nakazato Y
Brain tumor pathology 2014 Oct;31(4):257-64

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Molecular analysis of diffuse intrinsic brainstem gliomas in adults.

Reyes-Botero G, Giry M, Mokhtari K, Labussière M, Idbaih A, Delattre JY, Laigle-Donadey F, Sanson M
Journal of neuro-oncology 2014 Jan;116(2):405-11

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Immunohistochemical detection of IDH1 mutation, p53, and internexin as prognostic factors of glial tumors.

Takano S, Kato Y, Yamamoto T, Kaneko MK, Ishikawa E, Tsujimoto Y, Matsuda M, Nakai K, Yanagiya R, Morita S, Tsuboi K, Matsumura A
Journal of neuro-oncology 2012 Jul;108(3):361-73

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Fronto-temporal lobar degeneration: neuropathology in 60 cases.

Seilhean D, Le Ber I, Sarazin M, Lacomblez L, Millecamps S, Salachas F, Pradat PF, Le Forestier N, LeGuern E, Dubois B, Meininger V, Brice A, Hauw JJ, Duyckaerts C
Journal of neural transmission (Vienna, Austria : 1996) 2011 May;118(5):753-64

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Alpha-internexin expression predicts outcome in anaplastic oligodendroglial tumors and may positively impact the efficacy of chemotherapy: European organization for research and treatment of cancer trial 26951.

Mokhtari K, Ducray F, Kros JM, Gorlia T, Idbaih A, Taphoorn M, Wesseling P, Hoang-Xuan K, Van den Bent M, Sanson M
Cancer 2011 Jul 1;117(13):3014-26

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[Gliomatosis cerebri: a biopsy and autopsy case report].

San Millan B, Kaci R, Polivka M, Robert G, Héran F, Gueguen A, Mokhtari K, Gray F
Annales de pathologie 2010 Feb;30(1):25-9

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Expression of intermediate filament proteins and neuronal markers in the human fetal gut.

Rauch U, Klotz M, Maas-Omlor S, Wink E, Hänsgen A, Hagl C, Holland-Cunz S, Schäfer KH
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2006 Jan;54(1):39-46

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Neural expression of alpha-internexin promoter in vitro and in vivo.

Wang P, Wang SM, Hsieh CJ, Chien CL
Journal of cellular biochemistry 2006 Feb 1;97(2):275-87

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The expression of alpha-internexin and peripherin in the developing mouse pineal gland.

Ko TL, Chien CL, Lu KS
Journal of biomedical science 2005 Oct;12(5):777-89

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Screening for neurofilament inclusion disease using alpha-internexin immunohistochemistry.

Uchikado H, Shaw G, Wang DS, Dickson DW
Neurology 2005 May 10;64(9):1658-9

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Overexpression of neuronal intermediate filament protein alpha-internexin in PC12 cells.

Chien CL, Liu TC, Ho CL, Lu KS
Journal of neuroscience research 2005 Jun 1;80(5):693-706

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Extending the clinicopathological spectrum of neurofilament inclusion disease.

Josephs KA, Uchikado H, McComb RD, Bashir R, Wszolek Z, Swanson J, Matsumoto J, Shaw G, Dickson DW
Acta neuropathologica 2005 Apr;109(4):427-32

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p55 protein is a member of PSD scaffold proteins in the rat brain and interacts with various PSD proteins.

Jing-Ping Z, Tian QB, Sakagami H, Kondo H, Endo S, Suzuki T
Brain research. Molecular brain research 2005 Apr 27;135(1-2):204-16

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alpha-Internexin aggregates are abundant in neuronal intermediate filament inclusion disease (NIFID) but rare in other neurodegenerative diseases.

Cairns NJ, Uryu K, Bigio EH, Mackenzie IR, Gearing M, Duyckaerts C, Yokoo H, Nakazato Y, Jaros E, Perry RH, Arnold SE, Lee VM, Trojanowski JQ
Acta neuropathologica 2004 Sep;108(3):213-23

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Clinical and neuropathologic variation in neuronal intermediate filament inclusion disease.

Cairns NJ, Grossman M, Arnold SE, Burn DJ, Jaros E, Perry RH, Duyckaerts C, Stankoff B, Pillon B, Skullerud K, Cruz-Sanchez FF, Bigio EH, Mackenzie IR, Gearing M, Juncos JL, Glass JD, Yokoo H, Nakazato Y, Mosaheb S, Thorpe JR, Uryu K, Lee VM, Trojanowski JQ
Neurology 2004 Oct 26;63(8):1376-84

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alpha-internexin is present in the pathological inclusions of neuronal intermediate filament inclusion disease.

Cairns NJ, Zhukareva V, Uryu K, Zhang B, Bigio E, Mackenzie IR, Gearing M, Duyckaerts C, Yokoo H, Nakazato Y, Jaros E, Perry RH, Lee VM, Trojanowski JQ
The American journal of pathology 2004 Jun;164(6):2153-61

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Demonstration of natural autoantibodies against the neurofilament protein alpha-internexin in sera of patients with endocrine autoimmunity and healthy individuals.

Rajasalu T, Teesalu K, Janmey PA, Uibo R
Immunology letters 2004 Jun 15;94(1-2):153-60

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Neurofilament transport in vivo minimally requires hetero-oligomer formation.

Yuan A, Rao MV, Kumar A, Julien JP, Nixon RA
The Journal of neuroscience : the official journal of the Society for Neuroscience 2003 Oct 15;23(28):9452-8

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cAMP-induced differentiation of human neuronal progenitor cells is mediated by nuclear fibroblast growth factor receptor-1 (FGFR1).

Stachowiak EK, Fang X, Myers J, Dunham S, Stachowiak MK
Journal of neurochemistry 2003 Mar;84(6):1296-312

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Peripheral medulloepithelioma: an immunohistochemical, ultrastructural, and cytogenetic study of a rare, chemotherapy-sensitive, pediatric tumor.

Donner LR, Teshima I
The American journal of surgical pathology 2003 Jul;27(7):1008-12

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Substrates and routes of migration of early generated neurons in the developing rat thalamus.

Ortino B, Inverardi F, Morante-Oria J, Fairén A, Frassoni C
The European journal of neuroscience 2003 Jul;18(2):323-32

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Reduced number of unmyelinated sensory axons in peripherin null mice.

Larivière RC, Nguyen MD, Ribeiro-da-Silva A, Julien JP
Journal of neurochemistry 2002 May;81(3):525-32

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Preferential transformation of human neuronal cells by human adenoviruses and the origin of HEK 293 cells.

Shaw G, Morse S, Ararat M, Graham FL
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2002 Jun;16(8):869-71

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Axonally transported peripheral signals regulate alpha-internexin expression in regenerating motoneurons.

McGraw TS, Mickle JP, Shaw G, Streit WJ
The Journal of neuroscience : the official journal of the Society for Neuroscience 2002 Jun 15;22(12):4955-63

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Characterization of mitotic neurons derived from adult rat hypothalamus and brain stem.

Evans J, Sumners C, Moore J, Huentelman MJ, Deng J, Gelband CH, Shaw G
Journal of neurophysiology 2002 Feb;87(2):1076-85

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Spontaneous differentiation of porcine and bovine embryonic stem cells (epiblast) into astrocytes or neurons.

Talbot NC, Powell AM, Garrett WM
In vitro cellular & developmental biology. Animal 2002 Apr;38(4):191-7

Western blot

Supportive validation

Submitted by

antibodies-online (provider)

Main image

Experimental details

WB

Supportive validation

Submitted by

antibodies-online (provider)

Main image

Experimental details

WB

Supportive validation

Submitted by

antibodies-online (provider)

Main image

Experimental details

WB

Immunohistochemistry

Supportive validation

Submitted by

antibodies-online (provider)

Main image

Experimental details

IHC