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Protein structure
ASIC2
Acid sensing ion channel subunit 2ACCN, ACCN1, ASIC2a, BNaC1, BNC1, hBNaC1, MDEG
This gene encodes a member of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. The members of this family are amiloride-sensitive sodium channels that contain intracellular N and C termini, 2 hydrophobic transmembrane regions, and a large extracellular loop, which has many cysteine residues with conserved spacing. The member encoded by this gene may play a role in neurotransmission. In addition, a heteromeric association between this member and acid-sensing (proton-gated) ion channel 3 has been observed to co-assemble into proton-gated channels sensitive to gadolinium. Alternative splicing has been observed at this locus and two variants, encoding distinct isoforms, have been identified. [provided by RefSeq, Feb 2012]
Top validated antibodies |
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| Invitrogen Antibodies |  PA5-26222 |
2 references | Polyclonal |
WB
IHC
FC
OA
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| antibodies-online | ABIN2842729 |
1 references | Polyclonal |
WB
IHC
FC
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| Proteintech Group | 17851-1-AP |
2 references | Polyclonal |
WB
EL
IP
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| NSJ Bioreagents | RQ6038 |
Polyclonal |
WB
EL
ICC
FC
|
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| Boster Biological Technology | A04055-1 |
Polyclonal |
WB
EL
ICC
FC
|
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