Antibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations
- Western blot [1]
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- Product number
- PAB12121 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#PAB12121, RRID:AB_10554127
- Product name
- Lcat polyclonal antibody
- Antibody type
- Polyclonal
- Description
- Rabbit polyclonal antibody raised against partial recombinant Lcat.
- Storage
- Store at -20°C or -80°C.Aliquot to avoid repeated freezing and thawing.
Submitted references LCAT synthesized by primary astrocytes esterifies cholesterol on glia-derived lipoproteins.
Initial interaction of apoA-I with ABCA1 impacts in vivo metabolic fate of nascent HDL.
Functional LCAT deficiency in human apolipoprotein A-I transgenic, SR-BI knockout mice.
In vivo contribution of LCAT to apolipoprotein B lipoprotein cholesteryl esters in LDL receptor and apolipoprotein E knockout mice.
Lecithin:cholesterol acyltransferase deficiency increases atherosclerosis in the low density lipoprotein receptor and apolipoprotein E knockout mice.
Hirsch-Reinshagen V, Donkin J, Stukas S, Chan J, Wilkinson A, Fan J, Parks JS, Kuivenhoven JA, Lütjohann D, Pritchard H, Wellington CL
Journal of lipid research 2009 May;50(5):885-93
Journal of lipid research 2009 May;50(5):885-93
Initial interaction of apoA-I with ABCA1 impacts in vivo metabolic fate of nascent HDL.
Mulya A, Lee JY, Gebre AK, Boudyguina EY, Chung SK, Smith TL, Colvin PL, Jiang XC, Parks JS
Journal of lipid research 2008 Nov;49(11):2390-401
Journal of lipid research 2008 Nov;49(11):2390-401
Functional LCAT deficiency in human apolipoprotein A-I transgenic, SR-BI knockout mice.
Lee JY, Badeau RM, Mulya A, Boudyguina E, Gebre AK, Smith TL, Parks JS
Journal of lipid research 2007 May;48(5):1052-61
Journal of lipid research 2007 May;48(5):1052-61
In vivo contribution of LCAT to apolipoprotein B lipoprotein cholesteryl esters in LDL receptor and apolipoprotein E knockout mice.
Furbee JW Jr, Francone O, Parks JS
Journal of lipid research 2002 Mar;43(3):428-37
Journal of lipid research 2002 Mar;43(3):428-37
Lecithin:cholesterol acyltransferase deficiency increases atherosclerosis in the low density lipoprotein receptor and apolipoprotein E knockout mice.
Furbee JW Jr, Sawyer JK, Parks JS
The Journal of biological chemistry 2002 Feb 1;277(5):3511-9
The Journal of biological chemistry 2002 Feb 1;277(5):3511-9
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Supportive validation
- Submitted by
- Abnova Corporation (provider)
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- Experimental details
- Western blot analysis of plasma LCAT protein mass using Lcat polyclonal antibody (Cat # PAB12121). Plasma samples (0.2ul) from four hA-I Tg mice, four hA-I Tg SR-BI -/- mice, a LCAT-/- mouse, and purified mouse LCAT.