Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- PAB2319 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#PAB2319, RRID:AB_1580516
- Product name
- SGK2 polyclonal antibody
- Antibody type
- Polyclonal
- Description
- Rabbit polyclonal antibody raised against synthetic peptide of SGK2.
- Storage
- Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Submitted references The serine/threonine kinases SGK2 and SGK3 are potent stimulators of the epithelial Na+ channel alpha,beta,gamma-ENaC.
Regulation of KCNE1-dependent K(+) current by the serum and glucocorticoid-inducible kinase (SGK) isoforms.
K+ channel activation by all three isoforms of serum- and glucocorticoid-dependent protein kinase SGK.
Friedrich B, Feng Y, Cohen P, Risler T, Vandewalle A, Bröer S, Wang J, Pearce D, Lang F
Pflugers Archiv : European journal of physiology 2003 Mar;445(6):693-6
Pflugers Archiv : European journal of physiology 2003 Mar;445(6):693-6
Regulation of KCNE1-dependent K(+) current by the serum and glucocorticoid-inducible kinase (SGK) isoforms.
Embark HM, Böhmer C, Vallon V, Luft F, Lang F
Pflugers Archiv : European journal of physiology 2003 Feb;445(5):601-6
Pflugers Archiv : European journal of physiology 2003 Feb;445(5):601-6
K+ channel activation by all three isoforms of serum- and glucocorticoid-dependent protein kinase SGK.
Gamper N, Fillon S, Feng Y, Friedrich B, Lang PA, Henke G, Huber SM, Kobayashi T, Cohen P, Lang F
Pflugers Archiv : European journal of physiology 2002 Oct;445(1):60-6
Pflugers Archiv : European journal of physiology 2002 Oct;445(1):60-6
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Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Western blot analysis of SGK2 polyclonal antibody (Cat # PAB2319) in placenta lysate. SKG2 (arrow) was detected using purified polyclonal antibody. Secondary HRP-anti-rabbit was used for signal visualization with chemiluminescence.
Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Formalin-fixed and paraffin-embedded human cancer tissue reacted with the SGK2 polyclonal antibody (Cat # PAB2319) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry ; clinical relevance has not been evaluated. BC = breast carcinoma.
- Validation comment
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)