Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- PAB1938 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#PAB1938, RRID:AB_1579655
- Product name
- RCE1 polyclonal antibody
- Antibody type
- Polyclonal
- Description
- Rabbit polyclonal antibody raised against synthetic peptide of RCE1.
- Storage
- Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Submitted references A carboxyl-terminal interaction of lamin B1 is dependent on the CAAX endoprotease Rce1 and carboxymethylation.
Human Ras converting enzyme endoproteolytic specificity at the P2' and P3' positions of K-Ras-derived peptides.
Identification and chromosomal location of two human genes encoding enzymes potentially involved in proteolytic maturation of farnesylated proteins.
Maske CP, Hollinshead MS, Higbee NC, Bergo MO, Young SG, Vaux DJ
The Journal of cell biology 2003 Sep 29;162(7):1223-32
The Journal of cell biology 2003 Sep 29;162(7):1223-32
Human Ras converting enzyme endoproteolytic specificity at the P2' and P3' positions of K-Ras-derived peptides.
Hollander IJ, Frommer E, Aulabaugh A, Mallon R
Biochimica et biophysica acta 2003 Jun 26;1649(1):24-9
Biochimica et biophysica acta 2003 Jun 26;1649(1):24-9
Identification and chromosomal location of two human genes encoding enzymes potentially involved in proteolytic maturation of farnesylated proteins.
Freije JM, Blay P, Pendás AM, Cadiñanos J, Crespo P, López-Otín C
Genomics 1999 Jun 15;58(3):270-80
Genomics 1999 Jun 15;58(3):270-80
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Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Western blot analysis of RCE1 (arrow) using RCE1 polyclonal antibody (Cat # PAB1938).293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the RCE1 gene (Lane 2).
Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Formalin-fixed and paraffin-embedded human breast cancer tissue reacted with RCE1 polyclonal antibody (Cat # PAB1938) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
- Validation comment
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)