BS2558

antibody from Bioworld Technology, Inc

Targeting: CEBPG GPE1BP, IG/EBP-1

Western blot (Data presented on provider website)

Immunocytochemistry (Data presented on provider website)

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

BS2558

Provider

Bioworld Technology, Inc

Proper citation

Bioworld Technology Cat#BS2558, RRID:AB_1663545

Product name

C/EBP ÎÛ (E64) polyclonal antibody

Antibody type

Polyclonal

Antigen

Synthetic peptide, corresponding to amino acids 50-100 of Human C/EBP-ÎÛ.

Description

The transcription factor C/EBP Ï« (CCAAT-enhancer binding protein) is a heatstable, sequence-specific DNA-binding protein first purified from rat liver nuclei that binds avidly to several different cis-regulatory DNA sequences commonly associated with viral and cellular genes transcribed by RNA polymerase II. C/EBP Ï« regulates gene expression in a variety of tissues including liver, adipose, lung and intestine. C/EBP Ï« uses a bipartite structural motif to bind DNA. Two protein chains dimerize through a set of amphipathic alpha helices termed the leucine zipper. Highly basic polypeptide regions emerge from the zipper to form a linked set of DNA contact surfaces. C/EBP Ï« appears to function exclusively in terminally differentiated, growth-arrested cells. Additional family members include C/EBP ÉÇ, C/EBP ÎÛ,C/EBP Ñ´ and C/EBP š÷, all of which exhibit similar DNA-binding specificities and affinities to C/EBP Ï«. Furthermore, C/EBP ÉÇ and C/EBP Ñ´ readily form heterodimers both with each other as well as with C/EBP Ï«.

Reactivity

Human, Mouse, Rat

Host

Rabbit

Isotype

IgG

Vial size

100ul

Concentration

1 mg/ml

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.