BS8806

antibody from Bioworld Technology, Inc

Targeting: CEBPG GPE1BP, IG/EBP-1

Western blot (Data presented on provider website)

Immunocytochemistry (Data presented on provider website)

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

BS8806

Provider

Bioworld Technology, Inc

Product name

C/EBP ÎÛ polyclonal antibody

Antibody type

Polyclonal

Antigen

CCAAT/enhancer-binding protein gamma; C/EBP gamma; CEBPG; C/EBPÎÛ; CEBPÎÛ

Description

The transcription factor C/EBP Ï« (CCAAT-enhancer binding protein) is a heatstable, sequence-specific DNA-binding protein first purified from rat liver nuclei that binds avidly to several different cis-regulatory DNA sequences commonly associated with viral and cellular genes transcribed by RNA polymerase II. C/EBP Ï« regulates gene expression in a variety of tissues including liver, adipose, lung and intestine. C/EBP Ï« uses a bipartite structural motif to bind DNA. Two protein chains dimerize through a set of amphipathic alpha helices termed the leucine zipper. Highly basic polypeptide regions emerge from the zipper to form a linked set of DNA contact surfaces. C/EBP Ï« appears to function exclusively in terminally differentiated, growth-arrested cells. Additional family members include C/EBP ÉÇ, C/EBP ÎÛ,C/EBP Ñ´ and C/EBP š÷, all of which exhibit similar DNA-binding specificities and affinities to C/EBP Ï«. Furthermore, C/EBP ÉÇ and C/EBP Ñ´ readily form heterodimers both with each other as well as with C/EBP Ï«.

Reactivity

Human, Mouse, Rat

Host

Rabbit

Isotype

IgG

Vial size

100ul

Concentration

1 mg/ml

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.