CYP2A13

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum. Although its endogenous substrate has not been determined, it is known to metabolize 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone, a major nitrosamine specific to tobacco. This gene is part of a large cluster of cytochrome P450 genes from the CYP2A, CYP2B and CYP2F subfamilies on chromosome 19q. [provided by RefSeq, Jul 2008]

Description

Cytochrome P450 family 2 subfamily A member 13

Tissue specificity

Tissue enriched (liver)

Predicted location

Intracellular

Protein family

Enzymes
Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Metabolic proteins
Predicted intracellular proteins

Chromosome

19 (41088451 - 41096195)

Ensembl ID

ENSG00000197838  (ver. 103.38)

Orthologs

-

UniProt

Q16696

neXtProt

NX_Q16696

Human splice variants

Protein structure