GPR85

Members of the G protein-coupled receptor (GPCR) family, such as GPR85, have a similar structure characterized by 7 transmembrane domains. Activation of GPCRs by extracellular stimuli, such as neurotransmitters, hormones, or light, induces an intracellular signaling cascade mediated by heterotrimeric GTP-binding proteins, or G proteins (Matsumoto et al., 2000 [PubMed 10833454]). [supplied by OMIM, Aug 2008]

Description

G protein-coupled receptor 85

Protein family

G-protein coupled receptors, Mapped to neXtProt, Mapped to UniProt SWISS-PROT, Predicted membrane proteins

Chromosome

7:q31.1 (113078331 - 113087778)

Ensembl ID

ENSG00000164604  (ver. 99.38)

Orthologs

Mouse Gpr85: ENSMUSG00000048216

UniProt

P60893

neXtProt

NX_P60893

Human splice variants
Mouse splice variants