WDR25

This gene encodes a protein containing 7 WD repeats. WD repeats are approximately 30 to 40-amino acid domains containing several conserved residues, typically having a Tryptophan-Aspartic acid dipeptide (WD) at the C-terminal end. WD domains are involved in protein-protein interactions in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2017]

Description

WD repeat domain 25

Tissue specificity

Low tissue specificity

Subcell location

Nucleoplasm

Predicted location

Intracellular, Secreted to blood

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted intracellular proteins
Predicted secreted proteins
Protein evidence (Kim et al 2014)

Chromosome

14 (100376418 - 100530303)

Ensembl ID

ENSG00000176473  (ver. 103.38)

Orthologs

Mouse Wdr25: ENSMUSG00000040877

UniProt

Q64LD2

neXtProt

NX_Q64LD2

Human splice variants
Mouse splice variants

Protein structure