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antibody from antibodies-online
Targeting: WWTR1
DKFZp586I1419, TAZ
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- Antigen structure
- References [6]
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- Western blot [2]
- Immunohistochemistry [1]
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- Product number
- ABIN258561 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-WW Domain Containing Transcription Regulator 1 (WWTR1) antibody
- Antibody type
- Polyclonal
- Description
- Immunogen affinity purified
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Vial size
- 0.1 mL
- Storage
- Aliquot and store at -20°C or -80°C. Avoid freeze-thaw cycles.
- Handling
- Avoid freeze-thaw cycles
Submitted references A reciprocal regulatory loop between TAZ/YAP and G-protein Gαs regulates Schwann cell proliferation and myelination.
HIF-1α and TAZ serve as reciprocal co-activators in human breast cancer cells.
Hypoxia-inducible factor 1 mediates TAZ expression and nuclear localization to induce the breast cancer stem cell phenotype.
TAZ/WWTR1 is overexpressed in papillary thyroid carcinoma.
Human transcriptional coactivator with PDZ-binding motif (TAZ) is downregulated during decidualization.
The Hippo pathway regulates Wnt/beta-catenin signaling.
Deng Y, Wu LMN, Bai S, Zhao C, Wang H, Wang J, Xu L, Sakabe M, Zhou W, Xin M, Lu QR
Nature communications 2017 Apr 26;8:15161
Nature communications 2017 Apr 26;8:15161
HIF-1α and TAZ serve as reciprocal co-activators in human breast cancer cells.
Xiang L, Gilkes DM, Hu H, Luo W, Bullen JW, Liang H, Semenza GL
Oncotarget 2015 May 20;6(14):11768-78
Oncotarget 2015 May 20;6(14):11768-78
Hypoxia-inducible factor 1 mediates TAZ expression and nuclear localization to induce the breast cancer stem cell phenotype.
Xiang L, Gilkes DM, Hu H, Takano N, Luo W, Lu H, Bullen JW, Samanta D, Liang H, Semenza GL
Oncotarget 2014 Dec 30;5(24):12509-27
Oncotarget 2014 Dec 30;5(24):12509-27
TAZ/WWTR1 is overexpressed in papillary thyroid carcinoma.
de Cristofaro T, Di Palma T, Ferraro A, Corrado A, Lucci V, Franco R, Fusco A, Zannini M
European journal of cancer (Oxford, England : 1990) 2011 Apr;47(6):926-33
European journal of cancer (Oxford, England : 1990) 2011 Apr;47(6):926-33
Human transcriptional coactivator with PDZ-binding motif (TAZ) is downregulated during decidualization.
Strakova Z, Reed J, Ihnatovych I
Biology of reproduction 2010 Jun;82(6):1112-8
Biology of reproduction 2010 Jun;82(6):1112-8
The Hippo pathway regulates Wnt/beta-catenin signaling.
Varelas X, Miller BW, Sopko R, Song S, Gregorieff A, Fellouse FA, Sakuma R, Pawson T, Hunziker W, McNeill H, Wrana JL, Attisano L
Developmental cell 2010 Apr 20;18(4):579-91
Developmental cell 2010 Apr 20;18(4):579-91
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Supportive validation
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- antibodies-online (provider)
- Main image
- Experimental details
- WB
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- WB
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- IHC
