MA1-35677

antibody from Invitrogen Antibodies
Targeting: ABCC2 CMOAT, cMRP, DJS, MRP2
Provider product page for MA1-35677
Western blot
Immunohistochemistry

Antibody data

Product number
MA1-35677 - Provider product page
Provider
Invitrogen Antibodies
Product name
MRP2 Monoclonal Antibody (M2II-12)
Antibody type
Monoclonal
Antigen
Other
Description
M2II-12 reacts with an internal epitope of cMOAT/MRP2, a 190-200 kD transmembrane protein known as the canalicular multi-organic anion transporter, absent in patients with the Dubin-Johnson syndrome, an autosomal recessive liver disorder characterized by chronic conjugated hyperbilirubinemia. cMOAT/MRP2 is closely related to the multidrug resistance related protein MRP, and cMOAT/MRP2 overexpression has been observed in a subset of cisplatin resistant cell lines. M2II-12 was raised against a bacterial fusion protein of cMOAB/MRP2, containing amino acids 860-950 of the protein. M2II-12 did not cross react with the human MDR1, MRP1, MRP3 and MRP5 gene products.
Reactivity
Human
Host
Mouse
Isotype
IgG
Antibody clone number
M2II-12
Vial size
1 mL
Concentration
250 µg/mL
Storage
4° C
ABCC2 protein structure - MA1-35677 shown in red.