Antibody data
- Antibody Data
- Antigen structure
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- Product number
- MA1-35677 - Provider product page
- Provider
- Invitrogen Antibodies
- Product name
- MRP2 Monoclonal Antibody (M2II-12)
- Antibody type
- Monoclonal
- Antigen
- Other
- Description
- M2II-12 reacts with an internal epitope of cMOAT/MRP2, a 190-200 kD transmembrane protein known as the canalicular multi-organic anion transporter, absent in patients with the Dubin-Johnson syndrome, an autosomal recessive liver disorder characterized by chronic conjugated hyperbilirubinemia. cMOAT/MRP2 is closely related to the multidrug resistance related protein MRP, and cMOAT/MRP2 overexpression has been observed in a subset of cisplatin resistant cell lines. M2II-12 was raised against a bacterial fusion protein of cMOAB/MRP2, containing amino acids 860-950 of the protein. M2II-12 did not cross react with the human MDR1, MRP1, MRP3 and MRP5 gene products.
- Reactivity
- Human
- Host
- Mouse
- Isotype
- IgG
- Antibody clone number
- M2II-12
- Vial size
- 1 mL
- Concentration
- 250 µg/mL
- Storage
- 4° C
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