10077-1-AP
antibody from Proteintech Group
Targeting: KPNB1
IMB1, Impnb, IPO1, IPOB, MGC2155, MGC2156, MGC2157, NTF97
Antibody data
- Antibody Data
- Antigen structure
- References [6]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
Reference
Comment
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- Product number
- 10077-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#10077-1-AP, RRID:AB_2133977
- Product name
- Importin Beta antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated Importin Beta antibody (Cat. #10077-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Neddylation of PTEN regulates its nuclear import and promotes tumor development.
African Swine Fever Virus MGF360-12L Inhibits Type I Interferon Production by Blocking the Interaction of Importin α and NF-κB Signaling Pathway.
Targeting KPNB1 overcomes TRAIL resistance by regulating DR5, Mcl-1 and FLIP in glioblastoma cells.
KPNB1 inhibition disrupts proteostasis and triggers unfolded protein response-mediated apoptosis in glioblastoma cells.
Phospholipid scramblase 1 interacts with influenza A virus NP, impairing its nuclear import and thereby suppressing virus replication.
Nuclear import of Nkx2-2 is mediated by multiple pathways.
Xie P, Peng Z, Chen Y, Li H, Du M, Tan Y, Zhang X, Lu Z, Cui CP, Liu CH, He F, Zhang L
Cell research 2021 Mar;31(3):291-311
Cell research 2021 Mar;31(3):291-311
African Swine Fever Virus MGF360-12L Inhibits Type I Interferon Production by Blocking the Interaction of Importin α and NF-κB Signaling Pathway.
Zhuo Y, Guo Z, Ba T, Zhang C, He L, Zeng C, Dai H
Virologica Sinica 2021 Apr;36(2):176-186
Virologica Sinica 2021 Apr;36(2):176-186
Targeting KPNB1 overcomes TRAIL resistance by regulating DR5, Mcl-1 and FLIP in glioblastoma cells.
Zhu ZC, Liu JW, Yang C, Li MJ, Wu RJ, Xiong ZQ
Cell death & disease 2019 Feb 11;10(2):118
Cell death & disease 2019 Feb 11;10(2):118
KPNB1 inhibition disrupts proteostasis and triggers unfolded protein response-mediated apoptosis in glioblastoma cells.
Zhu ZC, Liu JW, Li K, Zheng J, Xiong ZQ
Oncogene 2018 May;37(22):2936-2952
Oncogene 2018 May;37(22):2936-2952
Phospholipid scramblase 1 interacts with influenza A virus NP, impairing its nuclear import and thereby suppressing virus replication.
Luo W, Zhang J, Liang L, Wang G, Li Q, Zhu P, Zhou Y, Li J, Zhao Y, Sun N, Huang S, Zhou C, Chang Y, Cui P, Chen P, Jiang Y, Deng G, Bu Z, Li C, Jiang L, Chen H
PLoS pathogens 2018 Jan;14(1):e1006851
PLoS pathogens 2018 Jan;14(1):e1006851
Nuclear import of Nkx2-2 is mediated by multiple pathways.
Lin W, Xu P, Guo Y, Jia Q, Tao T
Biochemical and biophysical research communications 2017 Jan 22;482(4):1511-1516
Biochemical and biophysical research communications 2017 Jan 22;482(4):1511-1516
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse brain tissue were subjected to SDS PAGE followed by western blot with 10077-1-AP( KPNB1 Antibody) at dilution of 1:600
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The Importin beta antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human Importin beta. This antibody recognizes human, mouse, rat antigen. The Importin beta antibody has been validated for the following applications: ELISA, IHC, WB analysis.