NB100-1277

De Cian MC, Gregoire EP, Le Rolle M, Lachambre S, Mondin M, Bell S, Guigon CJ, Chassot AA, Chaboissier MC
Cell death and differentiation 2020 Oct;27(10):2856-2871

Sox8 and Sox9 act redundantly for ovarian-to-testicular fate reprogramming in the absence of R-spondin1 in mouse sex reversals.

Richardson N, Gillot I, Gregoire EP, Youssef SA, de Rooij D, de Bruin A, De Cian MC, Chaboissier MC
eLife 2020 May 26;9

Generation of human oogonia from induced pluripotent stem cells in culture.

Yamashiro C, Sasaki K, Yokobayashi S, Kojima Y, Saitou M
Nature protocols 2020 Apr;15(4):1560-1583

FOXO1 Negates the Cooperative Action of FOXL2^C134W and SMAD3 in CYP19 Expression in HGrC1 Cells by Sequestering SMAD3.

Belli M, Secchi C, Stupack D, Shimasaki S
Journal of the Endocrine Society 2019 Nov 1;3(11):2064-2081

CBX2 is required to stabilize the testis pathway by repressing Wnt signaling.

Garcia-Moreno SA, Lin YT, Futtner CR, Salamone IM, Capel B, Maatouk DM
PLoS genetics 2019 May;15(5):e1007895

Ovarian stromal cells as a source of cancer-associated fibroblasts in human epithelial ovarian cancer: A histopathological study.

Fujisawa M, Moh-Moh-Aung A, Zeng Z, Yoshimura T, Wani Y, Matsukawa A
PloS one 2018;13(10):e0205494

Reproductive, Physiological, and Molecular Outcomes in Female Mice Deficient in Dhh and Ihh.

Liu C, Rodriguez KF, Brown PR, Yao HH
Endocrinology 2018 Jul 1;159(7):2563-2575

'Microcystic pattern' should be recognised as part of the morphological spectrum of solid-pseudopapillary neoplasm of the pancreas.

Abe A, Ohishi Y, Miyazaki T, Ozono K, Mochidome N, Saeki K, Nakamura M, Oda Y
Histopathology 2018 Jan;72(2):216-226

Genome-wide identification of FOXL2 binding and characterization of FOXL2 feminizing action in the fetal gonads.

Nicol B, Grimm SA, Gruzdev A, Scott GJ, Ray MK, Yao HH
Human molecular genetics 2018 Dec 15;27(24):4273-4287

FOXL2C134W-Induced CYP19 Expression via Cooperation With SMAD3 in HGrC1 Cells.

Belli M, Iwata N, Nakamura T, Iwase A, Stupack D, Shimasaki S
Endocrinology 2018 Apr 1;159(4):1690-1703

Expression of Kisspeptin in Gonadotrope Precursors in the Mouse Pituitary during Embryonic and Postnatal Development and in Adulthood.

Ikeda Y, Tagami A, Komada M, Takahashi M
Neuroendocrinology 2017;105(4):357-371

Normal Levels of Sox9 Expression in the Developing Mouse Testis Depend on the TES/TESCO Enhancer, but This Does Not Act Alone.

Gonen N, Quinn A, O'Neill HC, Koopman P, Lovell-Badge R
PLoS genetics 2017 Jan;13(1):e1006520

GLI1⁺ progenitor cells in the adrenal capsule of the adult mouse give rise to heterotopic gonadal-like tissue.

Dörner J, Martinez Rodriguez V, Ziegler R, Röhrig T, Cochran RS, Götz RM, Levin MD, Pihlajoki M, Heikinheimo M, Wilson DB
Molecular and cellular endocrinology 2017 Feb 5;441:164-175

Reconstitution in vitro of the entire cycle of the mouse female germ line.

Hikabe O, Hamazaki N, Nagamatsu G, Obata Y, Hirao Y, Hamada N, Shimamoto S, Imamura T, Nakashima K, Saitou M, Hayashi K
Nature 2016 Nov 10;539(7628):299-303

ADAM10-Notch signaling governs the recruitment of ovarian pregranulosa cells and controls folliculogenesis in mice.

Feng L, Wang Y, Cai H, Sun G, Niu W, Xin Q, Tang X, Zhang J, Wang C, Zhang H, Xia G
Journal of cell science 2016 Jun 1;129(11):2202-12

Uterine Tumor Resembling Ovarian Sex Cord Tumor (UTROSCT) Commonly Exhibits Positivity With Sex Cord Markers FOXL2 and SF-1 but Lacks FOXL2 and DICER1 Mutations.

Croce S, de Kock L, Boshari T, Hostein I, Velasco V, Foulkes WD, McCluggage WG
International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists 2016 Jul;35(4):301-8

Meiotic onset is reliant on spatial distribution but independent of germ cell number in the mouse ovary.

Arora R, Abby E, Ross AD, Cantu AV, Kissner MD, Castro V, Ho HY, Livera G, Laird DJ
Journal of cell science 2016 Jul 1;129(13):2493-9

Is there a robust future for research in reproduction?

Barratt CL
Molecular human reproduction 2016 Jan;22(1):1-2

A grafted ovarian fragment rescues host fertility after chemotherapy.

Batchvarov IS, Taylor RW, Bustamante-Marín X, Czerwinski M, Johnson ES, Kornbluth S, Capel B
Molecular human reproduction 2016 Dec;22(12):842-851

Juvenile granulosa cell tumors of the testis: a clinicopathologic study of 70 cases with emphasis on its wide morphologic spectrum.

Kao CS, Cornejo KM, Ulbright TM, Young RH
The American journal of surgical pathology 2015 Sep;39(9):1159-69

Novel markers of gonadectomy-induced adrenocortical neoplasia in the mouse and ferret.

Schillebeeckx M, Pihlajoki M, Gretzinger E, Yang W, Thol F, Hiller T, Löbs AK, Röhrig T, Schrade A, Cochran R, Jay PY, Heikinheimo M, Mitra RD, Wilson DB
Molecular and cellular endocrinology 2015 Jan 5;399:122-30

S100A8, An Oocyte-Specific Chemokine, Directs the Migration of Ovarian Somatic Cells During Mouse Primordial Follicle Assembly.

Teng Z, Wang C, Wang Y, Huang K, Xiang X, Niu W, Feng L, Zhao L, Yan H, Zhang H, Xia G
Journal of cellular physiology 2015 Dec;230(12):2998-3008

FOXL2, GATA4, and SMAD3 co-operatively modulate gene expression, cell viability and apoptosis in ovarian granulosa cell tumor cells.

Anttonen M, Pihlajoki M, Andersson N, Georges A, L'hôte D, Vattulainen S, Färkkilä A, Unkila-Kallio L, Veitia RA, Heikinheimo M
PloS one 2014;9(1):e85545

Uterine tumors resembling ovarian sex cord tumors (UTROSCT) with metastasis: clinicopathological study of two cases.

Umeda S, Tateno M, Miyagi E, Sakurai K, Tanaka R, Tateishi Y, Tokinaga A, Ohashi K, Furuya M
International journal of clinical and experimental pathology 2014;7(3):1051-9

The expression of FOXL2 in pancreatic, hepatobiliary, and renal tumors with ovarian-type stroma.

Westerhoff M, Tretiakova M, Hart J, Gwin K, Liu X, Zhou M, Yeh MM, Antic T
Human pathology 2014 May;45(5):1010-4

Impact of a second opinion using expression and molecular analysis of FOXL2 for sex cord-stromal tumors. A study of the GINECO group & the TMRO network.

Maillet D, Goulvent T, Rimokh R, Vacher-Lavenu MC, Pautier P, Alexandre J, Pujade-Laurraine E, Devouassoux-Shisheboran M, Treilleux I, Ray-Coquard I, Savina A
Gynecologic oncology 2014 Jan;132(1):181-7

A current perspective on the pathological assessment of FOXL2 in adult-type granulosa cell tumours of the ovary.

Kommoss S, Gilks CB, Penzel R, Herpel E, Mackenzie R, Huntsman D, Schirmacher P, Anglesio M, Schmidt D, Kommoss F
Histopathology 2014 Feb;64(3):380-8

Gonadoblastoma: an immunohistochemical study and comparison to Sertoli cell nodule with intratubular germ cell neoplasia, with pathogenetic implications.

Kao CS, Ulbright TM, Idrees MT
Histopathology 2014 Dec;65(6):861-7

Novel domains of expression for orphan receptor tyrosine kinase Ror2 in the human and mouse reproductive system.

Arora R, Altman E, Tran ND, Laird DJ
Developmental dynamics : an official publication of the American Association of Anatomists 2014 Aug;243(8):1037-45

Germ cells are not required to establish the female pathway in mouse fetal gonads.

Maatouk DM, Mork L, Hinson A, Kobayashi A, McMahon AP, Capel B
PloS one 2012;7(10):e47238

Testis development requires the repression of Wnt4 by Fgf signaling.

Jameson SA, Lin YT, Capel B
Developmental biology 2012 Oct 1;370(1):24-32

Temporal differences in granulosa cell specification in the ovary reflect distinct follicle fates in mice.

Mork L, Maatouk DM, McMahon JA, Guo JJ, Zhang P, McMahon AP, Capel B
Biology of reproduction 2012 Feb;86(2):37

Adrenergic regulation of AMP-activated protein kinase in brown adipose tissue in vivo.

Pulinilkunnil T, He H, Kong D, Asakura K, Peroni OD, Lee A, Kahn BB
The Journal of biological chemistry 2011 Mar 18;286(11):8798-809

FOXL2 is a sensitive and specific marker for sex cord-stromal tumors of the ovary.

Al-Agha OM, Huwait HF, Chow C, Yang W, Senz J, Kalloger SE, Huntsman DG, Young RH, Gilks CB
The American journal of surgical pathology 2011 Apr;35(4):484-94

The FOXL2 C134W mutation is characteristic of adult granulosa cell tumors of the ovary.

Jamieson S, Butzow R, Andersson N, Alexiadis M, Unkila-Kallio L, Heikinheimo M, Fuller PJ, Anttonen M
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2010 Nov;23(11):1477-85

Activin A regulates porcine follicle-stimulating hormone beta-subunit transcription via cooperative actions of SMADs and FOXL2.

Lamba P, Wang Y, Tran S, Ouspenskaia T, Libasci V, Hébert TE, Miller GJ, Bernard DJ
Endocrinology 2010 Nov;151(11):5456-67

FoxL2 and Smad3 coordinately regulate follistatin gene transcription.

Blount AL, Schmidt K, Justice NJ, Vale WW, Fischer WH, Bilezikjian LM
The Journal of biological chemistry 2009 Mar 20;284(12):7631-45

The putative forkhead transcription factor FOXL2 is mutated in blepharophimosis/ptosis/epicanthus inversus syndrome.

Crisponi L, Deiana M, Loi A, Chiappe F, Uda M, Amati P, Bisceglia L, Zelante L, Nagaraja R, Porcu S, Ristaldi MS, Marzella R, Rocchi M, Nicolino M, Lienhardt-Roussie A, Nivelon A, Verloes A, Schlessinger D, Gasparini P, Bonneau D, Cao A, Pilia G
Nature genetics 2001 Feb;27(2):159-66

No comments: Submit comment

Supportive validation

Submitted by: Novus Biologicals (provider)
Main image
Experimental details: Western Blot: FOXL2 Antibody [NB100-1277] - Staining of Human (A) and Mouse (B) Ovary lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Supportive validation

Submitted by: Novus Biologicals (provider)
Main image
Experimental details: Western Blot: FOXL2 Antibody [NB100-1277] - Staining of K562 cell lysate (A) + peptide (B) and HeLa cell lysate (C) + peptide (D) 35 ug protein in RIPA buffer). FOXL2 antibody at 2 ug/mL. Detected by chemiluminescence.

Supportive validation

Submitted by: Novus Biologicals (provider)
Main image
Experimental details: Immunohistochemistry-Paraffin: FOXL2 Antibody [NB100-1277] - (2ug/ml) staining of paraffin embedded Human Ovary. Steamed antigen retrieval with citrate buffer pH 6, HRP-staining.

Supportive validation

Submitted by: Novus Biologicals (provider)
Main image
Experimental details: Immunohistochemistry-Paraffin: FOXL2 Antibody [NB100-1277] - Staining of paraffin embedded Human Adrenal Gland. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.

Supportive validation

Submitted by: Novus Biologicals (provider)
Main image
Experimental details: Immunohistochemistry-Paraffin: FOXL2 Antibody [NB100-1277] - Staining of paraffin embedded Human Adrenal Gland. Antibody at 5 ug/mL. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.