SMARCA5

The protein encoded by this gene is a member of the SWI/SNF family of proteins. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The protein encoded by this gene is a component of the chromatin remodeling and spacing factor RSF, a facilitator of the transcription of class II genes by RNA polymerase II. The encoded protein is similar in sequence to the Drosophila ISWI chromatin remodeling protein. [provided by RefSeq, Jul 2008]

Description

SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5

Tissue specificity

Low tissue specificity

Subcell location

Nucleoplasm, Nucleoli fibrillar center

Predicted location

Intracellular

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Protein evidence (Kim et al 2014)
Transcription factors

Chromosome

4 (143513702 - 143557486)

Ensembl ID

ENSG00000153147  (ver. 103.38)

Orthologs

Mouse Smarca5: ENSMUSG00000031715

UniProt

O60264

neXtProt

NX_O60264

Human splice variants
Mouse splice variants

Protein structure