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Protein structure
KAT6B
Lysine acetyltransferase 6BMorf, MOZ2, MYST4, qkf, querkopf, ZC2HC6B
The protein encoded by this gene is a histone acetyltransferase and component of the MOZ/MORF protein complex. In addition to its acetyltransferase activity, the encoded protein has transcriptional activation activity in its N-terminal end and transcriptional repression activity in its C-terminal end. This protein is necessary for RUNX2-dependent transcriptional activation and could be involved in brain development. Mutations have been found in patients with genitopatellar syndrome. A translocation of this gene and the CREBBP gene results in acute myeloid leukemias. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2012]
Top validated antibodies |
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| Atlas Antibodies |  HPA006104 |
Polyclonal |
WB
ICC
IHC
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| Novus Biologicals | NBP1-92036 |
1 references | Polyclonal |
WB
ICC
IHC
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| Affinity Biosciences | DF8854 |
Polyclonal |
WB
EL
IHC
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| Biorbyt | orb948379 |
Polyclonal |
WB
ICC
IHC
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| LSBio | LS-C809895 |
Polyclonal |
WB
EL
IHC
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