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Protein structure
MTPN
MyotrophinGCDP, MYOTROPHIN, V-1
The transcript produced from this gene is bi-cistronic and can encode both myotrophin and leucine zipper protein 6. The myotrophin protein is associated with cardiac hypertrophy, where it is involved in the conversion of NFkappa B p50-p65 heterodimers to p50-p50 and p65-p65 homodimers. This protein also has a potential function in cerebellar morphogenesis, and it may be involved in the differentiation of cerebellar neurons, particularly of granule cells. A cryptic ORF at the 3' end of this transcript uses a novel internal ribosome entry site and a non-AUG translation initiation codon to produce leucine zipper protein 6, a 6.4 kDa tumor antigen that is associated with myeloproliferative disease. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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| Invitrogen Antibodies |  MA5-24520 |
Monoclonal |
WB
EL
ICC
OA
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| Proteintech Group | 13508-1-AP |
Polyclonal |
WB
EL
ICC
IHC
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| NovoPro Bioscience Inc. | 112794 |
Polyclonal |
WB
EL
ICC
IHC
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| Wuhan Fine Biotech Co., Ltd. | FNab05419 |
Polyclonal |
WB
EL
ICC
IHC
|
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| Novus Biologicals | H00136319-M14 |
Monoclonal |
WB
EL
ICC
|
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