CABT-B10108
antibody from Creative Diagnostics
Targeting: DMAP1
DNMAP1, DNMTAP1, EAF2, FLJ11543, KIAA1425, MEAF2, SWC4
Antibody data
- Antibody Data
- Antigen structure
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- Comments [0]
- Validations [0]
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- Product number
- CABT-B10108 - Provider product page
- Provider
- Creative Diagnostics
- Product name
- Mouse anti-Human DMAP1 monoclonal antibody, clone 3H23
- Antibody type
- Monoclonal
- Description
- This gene encodes a subunit of several, distinct complexes involved in the repression or activation of transcription. The encoded protein can independently repress transcription and is targeted to replication foci throughout S phase by interacting directly with the N-terminus of DNA methyltransferase 1. During late S phase, histone deacetylase 2 is added to this complex, providing a means to deacetylate histones in transcriptionally inactive heterochromatin following replication. The encoded protein is also a component of the nucleosome acetyltransferase of H4 complex and interacts with the transcriptional corepressor tumor susceptibility gene 101 and the pro-apoptotic death-associated protein 6, among others. Alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq, Jul 2008]
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Antibody clone number
- 3H23
- Storage
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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