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RAB7A
RAB7A, member RAS oncogene familyCMT2B, RAB7
RAB family members are small, RAS-related GTP-binding proteins that are important regulators of vesicular transport. Each RAB protein targets multiple proteins that act in exocytic / endocytic pathways. This gene encodes a RAB family member that regulates vesicle traffic in the late endosomes and also from late endosomes to lysosomes. This encoded protein is also involved in the cellular vacuolation of the VacA cytotoxin of Helicobacter pylori. Mutations at highly conserved amino acid residues in this gene have caused some forms of Charcot-Marie-Tooth (CMT) type 2 neuropathies. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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| Proteintech Group |  55469-1-AP |
26 references | Polyclonal |
WB
EL
IP
IHC
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| Invitrogen Antibodies | PA5-52369 |
3 references | Polyclonal |
WB
ICC
IHC
OA
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| GeneTex | GTX16196 |
2 references | Monoclonal |
WB
EL
ICC
IP
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| antibodies-online | ABIN2842407 |
1 references | Polyclonal |
WB
IHC
FC
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| Novus Biologicals | NBP1-87174 |
1 references | Polyclonal |
WB
ICC
IHC
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