OSBPL9

This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Most members contain an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain, although some members contain only the sterol-binding domain. This family member functions as a cholesterol transfer protein that regulates Golgi structure and function. Multiple transcript variants, most of which encode distinct isoforms, have been identified. Related pseudogenes have been identified on chromosomes 3, 11 and 12. [provided by RefSeq, Jul 2010]

Description

Oxysterol binding protein like 9

Tissue specificity

Low tissue specificity

Subcell location

Golgi apparatus, Vesicles

Predicted location

Intracellular

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Plasma proteins
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Protein evidence (Kim et al 2014)

Chromosome

1 (51577179 - 51798427)

Ensembl ID

ENSG00000117859  (ver. 103.38)

Orthologs

Mouse Osbpl9: ENSMUSG00000028559

UniProt

Q96SU4

neXtProt

NX_Q96SU4

Human splice variants
Mouse splice variants

Protein structure